Polaramine and Ascites - a phase IV clinical study of FDA data

Summary:

Ascites is reported as a side effect among people who take Polaramine (dexchlorpheniramine maleate), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Lasix, and have Renal cell carcinoma.

The phase IV clinical study analyzes which people have Ascites when taking Polaramine. It is created by eHealthMe based on reports of 10,478 people who have side effects when taking Polaramine from the FDA, and is updated regularly.

What is Polaramine?

Polaramine has active ingredients of dexchlorpheniramine maleate. It is often used in allergic rhinitis. eHealthMe is studying from 10,531 Polaramine users. Check the latest studies of Polaramine.

What is Ascites?

Ascites (accumulation of fluid in the abdominal cavity) is found to be associated with 1,534 drugs and 2,031 conditions by eHealthMe. Check the latest studies of Ascites.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

10,478 people reported to have side effects when taking Polaramine.
Among them, 31 people (0.3%) have Ascites.

Could Polaramine cause Ascites?

Among these 31 people:

How long have people been on Polaramine when they have Ascites? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ascites when taking Polaramine? *

  • female: 35.48 %
  • male: 64.52 %

What is the age of people who have Ascites when taking Polaramine? *

  • 0-1: 0.0 %
  • 2-9: 3.33 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10.0 %
  • 50-59: 46.67 %
  • 60+: 40.0 %

What are other drugs people take besides Polaramine? *

  1. Levofloxacin: 6 people, 19.35%
  2. Lasix: 6 people, 19.35%
  3. Naproxen: 5 people, 16.13%
  4. Voltaren: 5 people, 16.13%
  5. Lansoprazole: 5 people, 16.13%
  6. Taxol: 4 people, 12.90%
  7. Neupogen: 4 people, 12.90%
  8. Lorazepam: 4 people, 12.90%
  9. Solu-Medrol: 4 people, 12.90%
  10. Everolimus: 4 people, 12.90%

What are other side effects people have besides Ascites? *

  1. Pleural Effusion (water on the lungs): 15 people, 48.39%
  2. Hepatic Failure (liver failure): 9 people, 29.03%
  3. Hypotension (abnormally low blood pressure): 9 people, 29.03%
  4. Pneumonia: 9 people, 29.03%
  5. Delirium (wild excitement): 8 people, 25.81%
  6. Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 8 people, 25.81%
  7. Hepatorenal Syndrome (renal failure in patients with advanced chronic liver disease): 7 people, 22.58%
  8. Metastases To Lung (cancer spreads to lung): 7 people, 22.58%
  9. Metastases To Adrenals (cancer spreads to adrenal gland of kidney): 7 people, 22.58%
  10. Malaise (a feeling of general discomfort or uneasiness): 7 people, 22.58%

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 7 people, 22.58%
  2. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 4 people, 12.90%
  3. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 2 people, 6.45%
  4. Chronic Kidney Disease: 2 people, 6.45%
  5. Follicle Centre Lymphoma, Follicular Grade I, Ii, Iii Stage Iv: 2 people, 6.45%
  6. Itching: 2 people, 6.45%
  7. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 6.45%
  8. High Blood Pressure: 2 people, 6.45%
  9. Headache (pain in head): 1 person, 3.23%
  10. Constipation: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Polaramine and have Ascites?

- Check whether Ascites is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Polaramine:

Ascites treatments and more:

How severe was Ascites and when was it recovered:

Expand to all the drugs that have ingredients of dexchlorpheniramine maleate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Polaramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ascites:

Browse all the conditions that are associated with Ascites:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dexchlorpheniramine maleate (the active ingredients of Polaramine) and Polaramine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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