Pramipexole dihydrochloride and Myoclonus - a phase IV clinical study of FDA data

Summary:

Myoclonus is reported as a side effect among people who take Pramipexole dihydrochloride (pramipexole dihydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Lithium Carbonate, and have Suicidal ideation.

The phase IV clinical study analyzes which people have Myoclonus when taking Pramipexole dihydrochloride. It is created by eHealthMe based on reports of 5,315 people who have side effects when taking Pramipexole dihydrochloride from the FDA, and is updated regularly.

What is Pramipexole dihydrochloride?

Pramipexole dihydrochloride has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 5,670 Pramipexole dihydrochloride users. Check the latest studies of Pramipexole dihydrochloride.

What is Myoclonus?

Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles) is found to be associated with 760 drugs and 1,139 conditions by eHealthMe. Check the latest studies of Myoclonus.

On Jul, 05, 2026

5,315 people reported to have side effects when taking Pramipexole dihydrochloride.
Among them, 14 people (0.26%) have Myoclonus.

Could Pramipexole dihydrochloride cause Myoclonus?

Among these 14 people:

How long have people been on Pramipexole dihydrochloride when they have Myoclonus? *

What is the gender of people who have Myoclonus when taking Pramipexole dihydrochloride? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Myoclonus when taking Pramipexole dihydrochloride? *

What are other drugs people take besides Pramipexole dihydrochloride? *

What are other side effects people have besides Myoclonus? *

Movement - Uncoordinated: 7 people, 50.00%
Urinary Retention (the inability to completely or partially empty the bladder): 5 people, 35.71%
Hallucination, Visual (seeing things that aren't there): 5 people, 35.71%
Hypervigilance: 4 people, 28.57%
Dizziness: 4 people, 28.57%
Heart Rate Increased: 4 people, 28.57%
Feeling Jittery: 4 people, 28.57%
Blood Lactic Acid Increased: 4 people, 28.57%
Urination - Painful: 4 people, 28.57%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 21.43%

What are the existing conditions these people have? *

Suicidal Ideation: 3 people, 21.43%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 2 people, 14.29%
Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 7.14%
Stress And Anxiety: 1 person, 7.14%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 7.14%
Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 7.14%
Parkinsonian Rest Tremor: 1 person, 7.14%
Insomnia (sleeplessness): 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%
Depression: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Pramipexole dihydrochloride and have Myoclonus?

- Check whether Myoclonus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pramipexole dihydrochloride:

Pramipexole dihydrochloride (5,670 reports)

Myoclonus treatments and more:

Myoclonus (14,211 reports)

Browse all side effects of Pramipexole dihydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myoclonus:

Myoclonus (760 drugs)

Browse all the conditions that are associated with Myoclonus:

Myoclonus (1,139 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pramipexole dihydrochloride (the active ingredients of Pramipexole dihydrochloride) and Pramipexole dihydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.