Prednisolone and Anion gap increased - a phase IV clinical study of FDA data

Summary:

Anion gap increased is reported as a side effect among people who take Prednisolone (prednisolone), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Fluconazole, and have Arthritis.

The phase IV clinical study analyzes which people have Anion gap increased when taking Prednisolone. It is created by eHealthMe based on reports of 211,370 people who have side effects when taking Prednisolone from the FDA, and is updated regularly.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

What is Anion gap increased?

Anion gap increased is found to be associated with 249 drugs and 396 conditions by eHealthMe. Check the latest studies of Anion gap increased.



On Aug, 13, 2026

211,370 people reported to have side effects when taking Prednisolone.
Among them, 13 people (0.01%) have Anion gap increased.

Could Prednisolone cause Anion gap increased?

Among these 13 people:

How long have people been on Prednisolone when they have Anion gap increased? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Anion gap increased when taking Prednisolone? *

  • female: 58.33 %
  • male: 41.67 %

What is the age of people who have Anion gap increased when taking Prednisolone? *

  • 0-1: 9.09 %
  • 2-9: 0.0 %
  • 10-19: 9.09 %
  • 20-29: 0.0 %
  • 30-39: 27.27 %
  • 40-49: 18.18 %
  • 50-59: 9.09 %
  • 60+: 27.27 %

What are other drugs people take besides Prednisolone? *

  1. Fluconazole: 3 people, 23.08%
  2. Hydrocortisone: 2 people, 15.38%
  3. Rapamune: 2 people, 15.38%
  4. Eprex: 2 people, 15.38%
  5. Azathioprine: 2 people, 15.38%
  6. Tacrolimus: 2 people, 15.38%
  7. Paracetamol: 2 people, 15.38%
  8. Entresto: 1 person, 7.69%
  9. Enoxaparin Sodium: 1 person, 7.69%
  10. Enbrel: 1 person, 7.69%

What are other side effects people have besides Anion gap increased? *

  1. Blood Glucose Increased: 6 people, 46.15%
  2. Blood Creatinine Increased: 5 people, 38.46%
  3. Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 4 people, 30.77%
  4. Dehydration (dryness resulting from the removal of water): 3 people, 23.08%
  5. Fatigue (feeling of tiredness): 3 people, 23.08%
  6. Gamma-Glutamyltransferase Increased: 3 people, 23.08%
  7. Blood Urea Increased: 3 people, 23.08%
  8. Thirst - Excessive: 3 people, 23.08%
  9. Urination - Excessive Volume: 3 people, 23.08%
  10. Glycosylated Haemoglobin Increased: 2 people, 15.38%

What are the existing conditions these people have? *

  1. Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 1 person, 7.69%
  2. Spinal Muscular Atrophy (wasting of spinal muscles): 1 person, 7.69%
  3. Prostate Cancer: 1 person, 7.69%
  4. Interstitial Lung Disease: 1 person, 7.69%
  5. Immunodeficiency Disorders: 1 person, 7.69%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
  7. Febrile Neutropenia (fever with reduced white blood cells): 1 person, 7.69%
  8. Dizziness: 1 person, 7.69%
  9. Cardiac Sarcoidosis (an immune disorder): 1 person, 7.69%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisolone and have Anion gap increased?

- Check whether Anion gap increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prednisolone:

Anion gap increased treatments and more:

How severe was Anion gap increased and when was it recovered:

Expand to all the drugs that have ingredients of prednisolone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anion gap increased:

Browse all the conditions that are associated with Anion gap increased:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on prednisolone (the active ingredients of Prednisolone) and Prednisolone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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