Profen and Activated partial thromboplastin time shortened - a phase IV clinical study of FDA data

Summary:

Activated partial thromboplastin time shortened is reported as a side effect among people who take Profen (ibuprofen), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Fragmin, and have High blood pressure.

The phase IV clinical study analyzes which people have Activated partial thromboplastin time shortened when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Activated partial thromboplastin time shortened?

Activated partial thromboplastin time shortened is found to be associated with 82 drugs and 370 conditions by eHealthMe. Check the latest studies of Activated partial thromboplastin time shortened.

On Jul, 27, 2026

239,319 people reported to have side effects when taking Profen.
Among them, 16 people (0.01%) have Activated partial thromboplastin time shortened.

Could Profen cause Activated partial thromboplastin time shortened?

Among these 16 people:

How long have people been on Profen when they have Activated partial thromboplastin time shortened? *

What is the gender of people who have Activated partial thromboplastin time shortened when taking Profen? *

female: 50 %
male: 50 %

What is the age of people who have Activated partial thromboplastin time shortened when taking Profen? *

What are other drugs people take besides Profen? *

What are other side effects people have besides Activated partial thromboplastin time shortened? *

Nausea (feeling of having an urge to vomit): 8 people, 50.00%
White Blood Cell Count Increased: 6 people, 37.50%
Haemoglobin Decreased: 6 people, 37.50%
Thrombocytopenia (decrease of platelets in blood): 6 people, 37.50%
Oedema (fluid collection in tissue): 5 people, 31.25%
Red Blood Cell Count Decreased: 5 people, 31.25%
Insomnia (sleeplessness): 5 people, 31.25%
Haematocrit Decreased: 5 people, 31.25%
Glomerular Filtration Rate Decreased: 5 people, 31.25%
Gamma-Glutamyltransferase Increased: 5 people, 31.25%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 18.75%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 18.75%
High Blood Pressure: 3 people, 18.75%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 2 people, 12.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 12.50%
Upper Respiratory Tract Infection: 2 people, 12.50%
Pathogen Resistance: 2 people, 12.50%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 6.25%
Ill-Defined Disorder: 1 person, 6.25%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Activated partial thromboplastin time shortened?

- Check whether Activated partial thromboplastin time shortened is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Profen (245,311 reports)

Activated partial thromboplastin time shortened treatments and more:

Activated partial thromboplastin time shortened (694 reports)

How severe was Activated partial thromboplastin time shortened and when was it recovered:

Activated partial thromboplastin time shortened in Profen

Expand to all the drugs that have ingredients of ibuprofen:

Activated partial thromboplastin time shortened and drugs with ingredients of ibuprofen (22 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Activated partial thromboplastin time shortened:

Activated partial thromboplastin time shortened (82 drugs)

Browse all the conditions that are associated with Activated partial thromboplastin time shortened:

Activated partial thromboplastin time shortened (370 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.