Profen and Pancreatic enzymes increased - a phase IV clinical study of FDA data

Summary:

Pancreatic enzymes increased is reported as a side effect among people who take Profen (ibuprofen), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Promethazine, and have High blood pressure.

The phase IV clinical study analyzes which people have Pancreatic enzymes increased when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Pancreatic enzymes increased?

Pancreatic enzymes increased is found to be associated with 185 drugs and 409 conditions by eHealthMe. Check the latest studies of Pancreatic enzymes increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

239,319 people reported to have side effects when taking Profen.
Among them, 21 people (0.01%) have Pancreatic enzymes increased.

Could Profen cause Pancreatic enzymes increased?

Among these 21 people:

How long have people been on Profen when they have Pancreatic enzymes increased? *

What is the gender of people who have Pancreatic enzymes increased when taking Profen? *

female: 64.71 %
male: 35.29 %

What is the age of people who have Pancreatic enzymes increased when taking Profen? *

What are other drugs people take besides Profen? *

Ondansetron: 4 people, 19.05%
Nasonex: 4 people, 19.05%
Hydrocodone Bitartrate And Acetaminophen: 4 people, 19.05%
Aricept: 4 people, 19.05%
Klor-Con: 4 people, 19.05%
Zymaxid: 4 people, 19.05%
Toradol: 4 people, 19.05%
Septra Ds: 4 people, 19.05%
Questran: 4 people, 19.05%
Promethazine: 4 people, 19.05%

What are other side effects people have besides Pancreatic enzymes increased? *

Leukocytosis (increased white blood cells): 7 people, 33.33%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 6 people, 28.57%
Nausea And Vomiting: 6 people, 28.57%
Rash Pruritic (redness with itching): 5 people, 23.81%
Acute Kidney Failure: 5 people, 23.81%
Hypotension (abnormally low blood pressure): 5 people, 23.81%
Celiac Disease - Sprue (a disease of the small intestine): 4 people, 19.05%
Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 4 people, 19.05%
Insomnia (sleeplessness): 4 people, 19.05%
Depression: 4 people, 19.05%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 23.81%
Insomnia (sleeplessness): 4 people, 19.05%
Depression: 4 people, 19.05%
Dysmenorrhea (painful menstruation): 4 people, 19.05%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 19.05%
Stress And Anxiety: 4 people, 19.05%
Birth Control: 3 people, 14.29%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 14.29%
Pharyngolaryngeal Pain: 3 people, 14.29%
Fever: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Pancreatic enzymes increased?

- Check whether Pancreatic enzymes increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Profen (245,311 reports)

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pancreatic enzymes increased:

Pancreatic enzymes increased (185 drugs)

Browse all the conditions that are associated with Pancreatic enzymes increased:

Pancreatic enzymes increased (409 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.