Profen and Xeroderma - a phase IV clinical study of FDA data

Summary:

Xeroderma is reported as a side effect among people who take Profen (ibuprofen), especially for people who are male, 2-9 old, also take Ilaris, and have Familial mediterranean fever.

The phase IV clinical study analyzes which people have Xeroderma when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,301 Profen users. Check the latest studies of Profen.

What is Xeroderma?

Xeroderma (dry skin include itching and red, cracked or flaky skin) is found to be associated with 61 drugs and 285 conditions by eHealthMe. Check the latest studies of Xeroderma.



On Oct, 03, 2025

239,319 people reported to have side effects when taking Profen.
Among them, 10 people (0.0%) have Xeroderma.

Could Profen cause Xeroderma?

Among these 10 people:

What is the gender of people who have Xeroderma when taking Profen? *

  • female: 33.33 %
  • male: 66.67 %

What is the age of people who have Xeroderma when taking Profen? *

  • 0-1: 0.0 %
  • 2-9: 66.67 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 22.22 %
  • 50-59: 0.0 %
  • 60+: 11.11 %

What are other drugs people take besides Profen? *

  1. Ilaris: 6 people, 60.00%
  2. Valproic Acid: 4 people, 40.00%
  3. Lansoprazole: 4 people, 40.00%
  4. Isoniazid: 4 people, 40.00%
  5. Paracetamol: 3 people, 30.00%
  6. Revlimid: 1 person, 10.00%
  7. Oxycodone: 1 person, 10.00%

What are other side effects people have besides Xeroderma? *

  1. Weakness: 6 people, 60.00%
  2. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 6 people, 60.00%
  3. Headache (pain in head): 6 people, 60.00%
  4. Urinary Tract Obstruction: 6 people, 60.00%
  5. Fever: 6 people, 60.00%
  6. Familial Mediterranean Fever (genetic disease recurring attacks of abdominal pain, fever, pleurisy, arthritis, and rash): 6 people, 60.00%
  7. Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 6 people, 60.00%
  8. C-Reactive Protein Increased: 6 people, 60.00%
  9. Bundle Branch Block Right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle): 6 people, 60.00%
  10. Blood Urea Increased: 6 people, 60.00%

What are the existing conditions these people have? *

  1. Migraine (headache): 6 people, 60.00%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 60.00%
  3. Familial Mediterranean Fever (genetic disease recurring attacks of abdominal pain, fever, pleurisy, arthritis, and rash): 6 people, 60.00%
  4. Urinary Tract Infection: 5 people, 50.00%
  5. Influenza Like Illness: 3 people, 30.00%
  6. Stress And Anxiety: 1 person, 10.00%
  7. Neoplasm Malignant (cancer tumour): 1 person, 10.00%
  8. Lymphoma (cancer that begins in immune system cells): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Xeroderma?

- Check whether Xeroderma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Xeroderma treatments and more:

How severe was Xeroderma and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Xeroderma:

Browse all the conditions that are associated with Xeroderma:

Drugs similar to Profen and Xeroderma :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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