Prolixin and Psychotic disorder - a phase IV clinical study of FDA data

Summary:

Psychotic disorder is reported as a side effect among people who take Prolixin (fluphenazine hydrochloride), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Depakote, and have Schizophrenia.

The phase IV clinical study analyzes which people have Psychotic disorder when taking Prolixin. It is created by eHealthMe based on reports of 1,227 people who have side effects when taking Prolixin from the FDA, and is updated regularly.

What is Prolixin?

Prolixin has active ingredients of fluphenazine hydrochloride. It is often used in schizoaffective disorder. eHealthMe is studying from 1,262 Prolixin users. Check the latest studies of Prolixin.

What is Psychotic disorder?

Psychotic disorder is found to be associated with 1,232 drugs and 1,471 conditions by eHealthMe. Check the latest studies of Psychotic disorder.

On Jul, 17, 2026

1,227 people reported to have side effects when taking Prolixin.
Among them, 51 people (4.16%) have Psychotic disorder.

Could Prolixin cause Psychotic disorder?

Among these 51 people:

How long have people been on Prolixin when they have Psychotic disorder? *

What is the gender of people who have Psychotic disorder when taking Prolixin? *

female: 30 %
male: 70 %

What is the age of people who have Psychotic disorder when taking Prolixin? *

What are other drugs people take besides Prolixin? *

What are other side effects people have besides Psychotic disorder? *

Delusion (a false belief or opinion): 11 people, 21.57%
Aggression: 10 people, 19.61%
Suicidal Ideation: 10 people, 19.61%
Agitation (state of anxiety or nervous excitement): 9 people, 17.65%
Depression: 8 people, 15.69%
Insomnia (sleeplessness): 7 people, 13.73%
Drug Ineffective: 7 people, 13.73%
Fatigue (feeling of tiredness): 7 people, 13.73%
Stress And Anxiety: 7 people, 13.73%
Feeling Abnormal: 6 people, 11.76%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 18 people, 35.29%
Agitation (state of anxiety or nervous excitement): 4 people, 7.84%
Quit Smoking: 4 people, 7.84%
Bipolar Disorder (mood disorder): 4 people, 7.84%
Insomnia (sleeplessness): 4 people, 7.84%
Stress And Anxiety: 3 people, 5.88%
Affective Disorder (mental disorder): 2 people, 3.92%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 2 people, 3.92%
Sleep Disorder: 2 people, 3.92%
Sedation: 2 people, 3.92%

* Approximation only. Some reports may have incomplete information.

Do you take Prolixin and have Psychotic disorder?

- Check whether Psychotic disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prolixin:

Prolixin (1,262 reports)

Browse all side effects of Prolixin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Psychotic disorder:

Psychotic disorder (1,232 drugs)

Browse all the conditions that are associated with Psychotic disorder:

Psychotic disorder (1,471 conditions)

Related publications that referenced our studies

Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on fluphenazine hydrochloride (the active ingredients of Prolixin) and Prolixin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.