Propylthiouracil and Hepatitis aggravated - a phase IV clinical study of FDA data

Summary:

Hepatitis aggravated is reported as a side effect among people who take Propylthiouracil (propylthiouracil), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Atenolol, and have Basedow's disease.

The phase IV clinical study analyzes which people have Hepatitis aggravated when taking Propylthiouracil. It is created by eHealthMe based on reports of 2,435 people who have side effects when taking Propylthiouracil from the FDA, and is updated regularly.

What is Propylthiouracil?

Propylthiouracil has active ingredients of propylthiouracil. It is often used in hyperthyroidism. eHealthMe is studying from 2,545 Propylthiouracil users. Check the latest studies of Propylthiouracil.

What is Hepatitis aggravated?

Hepatitis aggravated is found to be associated with 1,153 drugs and 433 conditions by eHealthMe. Check the latest studies of Hepatitis aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

2,435 people reported to have side effects when taking Propylthiouracil.
Among them, 21 people (0.86%) have Hepatitis aggravated.

Could Propylthiouracil cause Hepatitis aggravated?

Among these 21 people:

How long have people been on Propylthiouracil when they have Hepatitis aggravated? *

What is the gender of people who have Hepatitis aggravated when taking Propylthiouracil? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Hepatitis aggravated when taking Propylthiouracil? *

What are other drugs people take besides Propylthiouracil? *

Atenolol: 2 people, 9.52%
Zoloft: 1 person, 4.76%
Imipenem And Cilastatin: 1 person, 4.76%
Allopurinol: 1 person, 4.76%
Arava: 1 person, 4.76%
Atazanavir: 1 person, 4.76%
Captopril: 1 person, 4.76%
Ceftin: 1 person, 4.76%
Coumadin: 1 person, 4.76%
Crestor: 1 person, 4.76%

What are other side effects people have besides Hepatitis aggravated? *

Hepatic Failure (liver failure): 4 people, 19.05%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 3 people, 14.29%
Liver Function Tests Nos Abnormal: 3 people, 14.29%
Acute Hepatic Failure: 3 people, 14.29%
Hepatic Necrosis (large portions of liver die off due to severe liver disease): 3 people, 14.29%
Hepatomegaly (abnormal enlargement of the liver): 3 people, 14.29%
Nausea (feeling of having an urge to vomit): 3 people, 14.29%
Itching: 3 people, 14.29%
Fever: 2 people, 9.52%
Encephalopathy (functioning of the brain is affected by some agent or condition): 2 people, 9.52%

What are the existing conditions these people have? *

Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 4 people, 19.05%
Abdominal Pain: 2 people, 9.52%
Thyroid Diseases: 1 person, 4.76%
Adverse Drug Reaction: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Propylthiouracil and have Hepatitis aggravated?

- Check whether Hepatitis aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Propylthiouracil:

Propylthiouracil (2,545 reports)

Browse all side effects of Propylthiouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatitis aggravated:

Hepatitis aggravated (1,153 drugs)

Browse all the conditions that are associated with Hepatitis aggravated:

Hepatitis aggravated (433 conditions)

Related publications that referenced our studies

Ayturk S, Demir MV, Yaylac? S, Tamer A, "Propylthiouracil induced leukocytoclastic vasculitis: A rare manifestation", Indian journal of endocrinology and metabolism, 2013 Jan .
Ayturk S, Demir MV, Yaylac? S, Tamer A, "Propylthiouracil induced leukocytoclastic vasculitis: A rare manifestation", Indian journal of endocrinology and metabolism, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on propylthiouracil (the active ingredients of Propylthiouracil) and Propylthiouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.