Protonix and Demyelination - a phase IV clinical study of FDA data

Summary:

Demyelination is reported as a side effect among people who take Protonix (pantoprazole sodium), especially for people who are female, 50-59 old, also take Lorazepam, and have Nausea.

The phase IV clinical study analyzes which people have Demyelination when taking Protonix. It is created by eHealthMe based on reports of 130,073 people who have side effects when taking Protonix from the FDA, and is updated regularly.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

What is Demyelination?

Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function) is found to be associated with 464 drugs and 669 conditions by eHealthMe. Check the latest studies of Demyelination.

On Jul, 16, 2026

130,073 people reported to have side effects when taking Protonix.
Among them, 35 people (0.03%) have Demyelination.

Among these 35 people:

What is the gender of people who have Demyelination when taking Protonix? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Demyelination when taking Protonix? *

What are other drugs people take besides Protonix? *

What are other side effects people have besides Demyelination? *

Fatigue (feeling of tiredness): 20 people, 57.14%
Depression: 19 people, 54.29%
Pain: 18 people, 51.43%
Stress And Anxiety: 17 people, 48.57%
Dizziness: 15 people, 42.86%
Upper Respiratory Tract Infection: 14 people, 40.00%
Nausea (feeling of having an urge to vomit): 14 people, 40.00%
Renal Cyst (kidney cyst): 13 people, 37.14%
Weakness: 12 people, 34.29%
Diarrhea: 12 people, 34.29%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 8 people, 22.86%
Hepatitis C: 7 people, 20.00%
Pain: 7 people, 20.00%
Depression: 5 people, 14.29%
High Blood Pressure: 5 people, 14.29%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 11.43%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 11.43%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 8.57%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 8.57%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

Do you take Protonix and have Demyelination?

- Check whether Demyelination is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Protonix:

Protonix (132,658 reports)

Demyelination treatments and more:

Demyelination (5,739 reports)

Browse all side effects of Protonix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Demyelination:

Demyelination (464 drugs)

Browse all the conditions that are associated with Demyelination:

Demyelination (669 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pantoprazole sodium (the active ingredients of Protonix) and Protonix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.