Qsymia and Glaucoma - a phase IV clinical study of FDA data

Summary:

Glaucoma is reported as a side effect among people who take Qsymia (phentermine hydrochloride; topiramate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Flexeril, and have Weight decreased.

The phase IV clinical study analyzes which people have Glaucoma when taking Qsymia. It is created by eHealthMe based on reports of 4,445 people who have side effects when taking Qsymia from the FDA, and is updated regularly.

What is Qsymia?

Qsymia has active ingredients of phentermine hydrochloride; topiramate. It is often used in weight loss. eHealthMe is studying from 4,530 Qsymia users. Check the latest studies of Qsymia.

What is Glaucoma?

Glaucoma (increased fluid pressure in the eye with vision loss) is found to be associated with 1,236 drugs and 1,654 conditions by eHealthMe. Check the latest studies of Glaucoma.

On Jul, 14, 2026

4,445 people reported to have side effects when taking Qsymia.
Among them, 13 people (0.29%) have Glaucoma.

Among these 13 people:

How long have people been on Qsymia when they have Glaucoma? *

What is the gender of people who have Glaucoma when taking Qsymia? *

female: 100 %
male: 0.0 %

What is the age of people who have Glaucoma when taking Qsymia? *

What are other drugs people take besides Qsymia? *

Flexeril: 1 person, 7.69%

What are other side effects people have besides Glaucoma? *

Ocular Discomfort (a generic expression when there is lack of ease in/about the eyes): 2 people, 15.38%
Vision Blurred: 2 people, 15.38%
Visual Acuity Reduced (reduced clearness of vision): 1 person, 7.69%
Headache (pain in head): 1 person, 7.69%
Blindness Transient (sudden loss of vision): 1 person, 7.69%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 7.69%
Discomfort: 1 person, 7.69%
Dizziness: 1 person, 7.69%
Eye Pain: 1 person, 7.69%
Eyelid Twitch (spontaneous and uncontrolled spasms of the muscles): 1 person, 7.69%

What are the existing conditions these people have? *

Weight Decreased: 7 people, 53.85%
Type 2 Diabetes: 1 person, 7.69%
Joint Pain: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Qsymia and have Glaucoma?

- Check whether Glaucoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Qsymia:

Qsymia (4,530 reports)

Glaucoma treatments and more:

Glaucoma (61,926 reports)

How severe was Glaucoma and when was it recovered:

Glaucoma in Qsymia

Expand to all the drugs that have ingredients of phentermine hydrochloride; topiramate:

Glaucoma and drugs with ingredients of phentermine hydrochloride; topiramate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Qsymia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Glaucoma:

Glaucoma (1,236 drugs)

Browse all the conditions that are associated with Glaucoma:

Glaucoma (1,654 conditions)

Related publications that referenced our studies

Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on phentermine hydrochloride; topiramate (the active ingredients of Qsymia) and Qsymia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.