Ramipril and Optic atrophy - a phase IV clinical study of FDA data

Summary:

Optic atrophy is reported as a side effect among people who take Ramipril (ramipril), especially for people who are male, 30-39 old, also take Prograf, and have Hepatitis b.

The phase IV clinical study analyzes which people have Optic atrophy when taking Ramipril. It is created by eHealthMe based on reports of 144,209 people who have side effects when taking Ramipril from the FDA, and is updated regularly.

What is Ramipril?

Ramipril has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 147,398 Ramipril users. Check the latest studies of Ramipril.

What is Optic atrophy?

Optic atrophy (the loss of a proportion of optic disc nerve fibres) is found to be associated with 244 drugs and 453 conditions by eHealthMe. Check the latest studies of Optic atrophy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

144,209 people reported to have side effects when taking Ramipril.
Among them, 33 people (0.02%) have Optic atrophy.

Among these 33 people:

What is the gender of people who have Optic atrophy when taking Ramipril? *

female: 25.81 %
male: 74.19 %

What is the age of people who have Optic atrophy when taking Ramipril? *

What are other drugs people take besides Ramipril? *

Prograf: 20 people, 60.61%
Lamivudine: 12 people, 36.36%
Tacrolimus: 12 people, 36.36%
Methylprednisolone: 12 people, 36.36%
Prednisone: 12 people, 36.36%
Mycophenolate Mofetil: 12 people, 36.36%
Amlodipine: 9 people, 27.27%
Amlodipine Besylate: 9 people, 27.27%
Doxazosin Mesylate: 9 people, 27.27%
Pantoprazole Sodium: 3 people, 9.09%

What are other side effects people have besides Optic atrophy? *

Visual Field Defect: 21 people, 63.64%
Anaemia (lack of blood): 20 people, 60.61%
Toxic Neuropathy (nerve damage caused by toxic (harmful) substances): 20 people, 60.61%
Hyperthyroidism (over activity of the thyroid gland): 20 people, 60.61%
High Blood Cholesterol: 20 people, 60.61%
Optic Nerve Disorder (disease of optic nerve): 20 people, 60.61%
Hypertriglyceridaemia (excess of triglycerides in the blood): 20 people, 60.61%
Toxic Optic Neuropathy (optic nerve damage caused by toxic (harmful) substances): 19 people, 57.58%
Complications Of Transplanted Kidney: 18 people, 54.55%
Visual Acuity Reduced (reduced clearness of vision): 4 people, 12.12%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 20 people, 60.61%
Hyperlipidaemia (presence of excess lipids in the blood): 20 people, 60.61%
Hepatitis B: 20 people, 60.61%
Immunodeficiency Disorders: 4 people, 12.12%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 9.09%
Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 2 people, 6.06%
Sensory Disturbance (sense disturbance): 1 person, 3.03%
Pulmonary Tuberculosis (lungs tuberculosis): 1 person, 3.03%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 1 person, 3.03%
Neoplasm Malignant (cancer tumour): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Ramipril and have Optic atrophy?

- Check whether Optic atrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ramipril:

Ramipril (147,398 reports)

Optic atrophy treatments and more:

Optic atrophy (2,242 reports)

Browse all side effects of Ramipril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Optic atrophy:

Optic atrophy (244 drugs)

Browse all the conditions that are associated with Optic atrophy:

Optic atrophy (453 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ramipril (the active ingredients of Ramipril) and Ramipril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.