Ravicti and Weight increased - a phase IV clinical study of FDA data

Summary:

Weight increased is reported as a side effect among people who take Ravicti (glycerol phenylbutyrate), especially for people who are female, 10-19 old, have been taking the drug for 1 - 6 months also take Citrulline, and have Argininosuccinate synthetase deficiency.

The phase IV clinical study analyzes which people have Weight increased when taking Ravicti. It is created by eHealthMe based on reports of 1,197 people who have side effects when taking Ravicti from the FDA, and is updated regularly.

What is Ravicti?

Ravicti has active ingredients of glycerol phenylbutyrate. eHealthMe is studying from 1,197 Ravicti users. Check the latest studies of Ravicti.

What is Weight increased?

Weight increased is found to be associated with 2,885 drugs and 3,951 conditions by eHealthMe. Check the latest studies of Weight increased.

On Jul, 12, 2026

1,197 people reported to have side effects when taking Ravicti.
Among them, 24 people (2.01%) have Weight increased.

Among these 24 people:

How long have people been on Ravicti when they have Weight increased? *

What is the gender of people who have Weight increased when taking Ravicti? *

female: 55 %
male: 45 %

What is the age of people who have Weight increased when taking Ravicti? *

What are other drugs people take besides Ravicti? *

What are other side effects people have besides Weight increased? *

Ammonia Increased: 5 people, 20.83%
The Flu (the flu is caused by an influenza virus): 4 people, 16.67%
Hyperammonaemia: 4 people, 16.67%
Anaemia (lack of blood): 3 people, 12.50%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 12.50%
Hepatic Steatosis (fatty liver disease): 2 people, 8.33%
Nausea (feeling of having an urge to vomit): 2 people, 8.33%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 8.33%
Hepatic Function Abnormal: 2 people, 8.33%
Hepatic Mass: 2 people, 8.33%

What are the existing conditions these people have? *

Argininosuccinate Synthetase Deficiency: 3 people, 12.50%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 4.17%
Carbamoyl Phosphate Synthetase Deficiency (metabolic disorder that causes ammonia to accumulate in the blood): 1 person, 4.17%
Amino Acid Metabolism Disorder: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Ravicti and have Weight increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ravicti:

Ravicti (1,197 reports)

Weight increased treatments and more:

Weight increased (279,369 reports)

Browse all side effects of Ravicti:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight increased:

Weight increased (2,885 drugs)

Browse all the conditions that are associated with Weight increased:

Weight increased (3,951 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glycerol phenylbutyrate (the active ingredients of Ravicti) and Ravicti (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.