Repaglinide and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Repaglinide (repaglinide), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Metformin, and have High blood pressure.

The phase IV clinical study analyzes which people have Stroke when taking Repaglinide. It is created by eHealthMe based on reports of 8,187 people who have side effects when taking Repaglinide from the FDA, and is updated regularly.

What is Repaglinide?

Repaglinide has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 8,226 Repaglinide users. Check the latest studies of Repaglinide.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,380 drugs and 3,011 conditions by eHealthMe. Check the latest studies of Stroke.



On Dec, 22, 2025

8,187 people reported to have side effects when taking Repaglinide.
Among them, 47 people (0.57%) have Stroke.

Could Repaglinide cause Stroke?

Among these 47 people:

How long have people been on Repaglinide when they have Stroke? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 66.67 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Stroke when taking Repaglinide? *

  • female: 40.43 %
  • male: 59.57 %

What is the age of people who have Stroke when taking Repaglinide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 2.44 %
  • 50-59: 2.44 %
  • 60+: 95.12 %

What are other drugs people take besides Repaglinide? *

  1. Metformin: 12 people, 25.53%
  2. Lantus: 7 people, 14.89%
  3. Amlodipine: 6 people, 12.77%
  4. Aspirin: 6 people, 12.77%
  5. Insulin: 6 people, 12.77%
  6. Coumadin: 6 people, 12.77%
  7. Lyrica: 5 people, 10.64%
  8. Januvia: 5 people, 10.64%
  9. Cymbalta: 5 people, 10.64%
  10. Zyprexa: 4 people, 8.51%

What are other side effects people have besides Stroke? *

  1. Fever: 6 people, 12.77%
  2. Pain: 5 people, 10.64%
  3. Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 4 people, 8.51%
  4. Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 8.51%
  5. Herpes Zoster: 4 people, 8.51%
  6. Malaise (a feeling of general discomfort or uneasiness): 4 people, 8.51%
  7. Urinary Tract Infection: 4 people, 8.51%
  8. Febrile Neutropenia (fever with reduced white blood cells): 4 people, 8.51%
  9. Fatigue (feeling of tiredness): 4 people, 8.51%
  10. Eye Disorder: 4 people, 8.51%

What are the existing conditions these people have? *

  1. High Blood Pressure: 11 people, 23.40%
  2. Pain: 10 people, 21.28%
  3. Nausea (feeling of having an urge to vomit): 7 people, 14.89%
  4. Enlarged Prostate: 5 people, 10.64%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 10.64%
  6. Wound: 4 people, 8.51%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.51%
  8. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 4 people, 8.51%
  9. Infection: 4 people, 8.51%
  10. Delirium (wild excitement): 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

Do you take Repaglinide and have Stroke?

- Check whether Stroke is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
- Get an AI agent to monitor your drugs continuously (FREE)



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Repaglinide:

Stroke treatments and more:

How severe was Stroke and when was it recovered:

Expand to all the drugs that have ingredients of repaglinide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Repaglinide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Browse all the conditions that are associated with Stroke:

Drugs similar to Repaglinide and Stroke :


How the study uses the data?

The study uses data from the FDA. It is based on repaglinide (the active ingredients of Repaglinide) and Repaglinide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: