Restasis and Costochondritis - a phase IV clinical study of FDA data

Summary:

Costochondritis is reported as a side effect among people who take Restasis (cyclosporine), especially for people who are female, 50-59 old, have been taking the drug for 10+ years also take Vitamin C, and have Depression.

The phase IV clinical study analyzes which people have Costochondritis when taking Restasis. It is created by eHealthMe based on reports of 34,716 people who have side effects when taking Restasis from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Costochondritis?

Costochondritis (chest wall pain) is found to be associated with 412 drugs and 574 conditions by eHealthMe. Check the latest studies of Costochondritis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

34,716 people reported to have side effects when taking Restasis.
Among them, 15 people (0.04%) have Costochondritis.

Among these 15 people:

How long have people been on Restasis when they have Costochondritis? *

What is the gender of people who have Costochondritis when taking Restasis? *

female: 92.86 %
male: 7.14 %

What is the age of people who have Costochondritis when taking Restasis? *

What are other drugs people take besides Restasis? *

What are other side effects people have besides Costochondritis? *

Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 7 people, 46.67%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 6 people, 40.00%
Urinary Tract Infection: 6 people, 40.00%
Cough: 6 people, 40.00%
Chest Pain: 6 people, 40.00%
Speech Impairment (Adult) (inability to speak (adult)): 5 people, 33.33%
Pain: 5 people, 33.33%
Hypokalemia (low potassium): 5 people, 33.33%
Hypoaesthesia (reduced sense of touch or sensation): 5 people, 33.33%
Pneumonia: 5 people, 33.33%

What are the existing conditions these people have? *

Depression: 8 people, 53.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 26.67%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 26.67%
Back Pain: 4 people, 26.67%
Oedema Peripheral (superficial swelling): 4 people, 26.67%
Indigestion: 3 people, 20.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 20.00%
Osteoporosis (bones weak and more likely to break): 2 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
Head Injury: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Restasis and have Costochondritis?

- Check whether Costochondritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Restasis:

Restasis (35,199 reports)

Costochondritis treatments and more:

Costochondritis (3,005 reports)

Browse all side effects of Restasis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Costochondritis:

Costochondritis (412 drugs)

Browse all the conditions that are associated with Costochondritis:

Costochondritis (574 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Restasis) and Restasis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.