Restasis and Urination - excessive at night - a phase IV clinical study of FDA data

Summary:

Urination - excessive at night is reported as a side effect among people who take Restasis (cyclosporine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin D3, and have Pain.

The phase IV clinical study analyzes which people have Urination - excessive at night when taking Restasis. It is created by eHealthMe based on reports of 34,716 people who have side effects when taking Restasis from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Urination - excessive at night?

Urination - excessive at night is found to be associated with 1,073 drugs and 1,256 conditions by eHealthMe. Check the latest studies of Urination - excessive at night.

On Jul, 16, 2026

34,716 people reported to have side effects when taking Restasis.
Among them, 29 people (0.08%) have Urination - excessive at night.

Could Restasis cause Urination - excessive at night?

Among these 29 people:

How long have people been on Restasis when they have Urination - excessive at night? *

What is the gender of people who have Urination - excessive at night when taking Restasis? *

female: 86.21 %
male: 13.79 %

What is the age of people who have Urination - excessive at night when taking Restasis? *

What are other drugs people take besides Restasis? *

What are other side effects people have besides Urination - excessive at night? *

Fatigue (feeling of tiredness): 17 people, 58.62%
Weakness: 14 people, 48.28%
Joint Pain: 13 people, 44.83%
Dizziness: 13 people, 44.83%
Rashes (redness): 13 people, 44.83%
Headache (pain in head): 12 people, 41.38%
Muscle Aches (muscle pain): 11 people, 37.93%
Back Pain: 10 people, 34.48%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 10 people, 34.48%
Ear Pain: 10 people, 34.48%

What are the existing conditions these people have? *

Pain: 8 people, 27.59%
Urethritis Noninfective (inflammation of the urethra - non infective): 7 people, 24.14%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 24.14%
Bladder Disorder: 7 people, 24.14%
Blood Glucose Abnormal: 7 people, 24.14%
Cough: 7 people, 24.14%
Gait Disturbance: 7 people, 24.14%
Muscle Spasms (muscle contraction): 4 people, 13.79%
Diarrhea: 3 people, 10.34%
High Blood Cholesterol: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

Do you take Restasis and have Urination - excessive at night?

- Check whether Urination - excessive at night is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Restasis:

Restasis (35,199 reports)

Browse all side effects of Restasis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urination - excessive at night:

Urination - excessive at night (1,073 drugs)

Browse all the conditions that are associated with Urination - excessive at night:

Urination - excessive at night (1,256 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Restasis) and Restasis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.