Revatio and Multiple sclerosis aggravated - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis aggravated is reported as a side effect among people who take Revatio (sildenafil citrate), especially for people who are female, 40-49 old, have been taking the drug for 5 - 10 years also take Coumadin, and have High blood pressure.

The phase IV clinical study analyzes which people have Multiple sclerosis aggravated when taking Revatio. It is created by eHealthMe based on reports of 44,758 people who have side effects when taking Revatio from the FDA, and is updated regularly.

What is Revatio?

Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.

What is Multiple sclerosis aggravated?

Multiple sclerosis aggravated (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,020 drugs and 322 conditions by eHealthMe. Check the latest studies of Multiple sclerosis aggravated.

On Jul, 11, 2026

44,758 people reported to have side effects when taking Revatio.
Among them, 20 people (0.04%) have Multiple sclerosis aggravated.

Could Revatio cause Multiple sclerosis aggravated?

Among these 20 people:

How long have people been on Revatio when they have Multiple sclerosis aggravated? *

What is the gender of people who have Multiple sclerosis aggravated when taking Revatio? *

female: 84.21 %
male: 15.79 %

What is the age of people who have Multiple sclerosis aggravated when taking Revatio? *

What are other drugs people take besides Revatio? *

What are other side effects people have besides Multiple sclerosis aggravated? *

Fatigue (feeling of tiredness): 5 people, 25.00%
Pain In Extremity: 5 people, 25.00%
Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 20.00%
Weight Increased: 4 people, 20.00%
Haematuria (presence of blood in urine): 4 people, 20.00%
Memory Loss: 4 people, 20.00%
Wound Haemorrhage (bleeding wound): 4 people, 20.00%
Dry Skin: 3 people, 15.00%
Pain: 3 people, 15.00%
Nausea (feeling of having an urge to vomit): 3 people, 15.00%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 25.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 20.00%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 20.00%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 20.00%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 10.00%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 10.00%
Cyanotic Heart Disease (deoxygenated blood bypassing the lungs and entering the systemic circulation): 1 person, 5.00%
Diabetes: 1 person, 5.00%
Embolism Venous (embolus may pass into the arterial system): 1 person, 5.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Revatio and have Multiple sclerosis aggravated?

- Check whether Multiple sclerosis aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Revatio:

Revatio (44,849 reports)

Browse all side effects of Revatio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis aggravated:

Multiple sclerosis aggravated (1,021 drugs)

Browse all the conditions that are associated with Multiple sclerosis aggravated:

Multiple sclerosis aggravated (322 conditions)

Related publications that referenced our studies

Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on sildenafil citrate (the active ingredients of Revatio) and Revatio (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.