Reyvow and Insomnia exacerbated - a phase IV clinical study of FDA data

Summary:

Insomnia exacerbated is reported as a side effect among people who take Reyvow (lasmiditan succinate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Botox, and have Migraine.

The phase IV clinical study analyzes which people have Insomnia exacerbated when taking Reyvow. It is created by eHealthMe based on reports of 1,004 people who have side effects when taking Reyvow from the FDA, and is updated regularly.

What is Reyvow?

Reyvow has active ingredients of lasmiditan succinate. eHealthMe is studying from 1,006 Reyvow users. Check the latest studies of Reyvow.

What is Insomnia exacerbated?

Insomnia exacerbated (severe sleeplessness) is found to be associated with 2,650 drugs and 974 conditions by eHealthMe. Check the latest studies of Insomnia exacerbated.



On Jul, 13, 2026

1,004 people reported to have side effects when taking Reyvow.
Among them, 32 people (3.19%) have Insomnia exacerbated.

Could Reyvow cause Insomnia exacerbated?

Among these 32 people:

How long have people been on Reyvow when they have Insomnia exacerbated? *

  • < 1 month: 75 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Insomnia exacerbated when taking Reyvow? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Insomnia exacerbated when taking Reyvow? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 11.11 %
  • 30-39: 16.67 %
  • 40-49: 38.89 %
  • 50-59: 33.33 %
  • 60+: 0.0 %

What are other drugs people take besides Reyvow? *

  1. Botox: 8 people, 25.00%
  2. Vyepti: 7 people, 21.88%
  3. Nurtec Odt: 7 people, 21.88%
  4. Ubrelvy: 6 people, 18.75%
  5. Fioricet: 5 people, 15.62%
  6. Emgality: 4 people, 12.50%
  7. Toradol: 4 people, 12.50%
  8. Zomig: 3 people, 9.38%
  9. Medrol: 3 people, 9.38%
  10. Keppra: 3 people, 9.38%

What are other side effects people have besides Insomnia exacerbated? *

  1. Migraine (headache): 10 people, 31.25%
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 7 people, 21.88%
  3. Nausea (feeling of having an urge to vomit): 7 people, 21.88%
  4. Heart Rate Increased: 7 people, 21.88%
  5. Fatigue (feeling of tiredness): 6 people, 18.75%
  6. Dizziness: 6 people, 18.75%
  7. Stress And Anxiety: 6 people, 18.75%
  8. Headache (pain in head): 5 people, 15.62%
  9. Hallucinations (sensations that appear real but are created by your mind): 3 people, 9.38%
  10. Feeling Abnormal: 3 people, 9.38%

What are the existing conditions these people have? *

  1. Migraine (headache): 24 people, 75.00%
  2. Stress And Anxiety: 3 people, 9.38%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.25%
  4. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 2 people, 6.25%
  5. Nausea (feeling of having an urge to vomit): 2 people, 6.25%
  6. Blood Testosterone Increased: 2 people, 6.25%
  7. Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 2 people, 6.25%
  8. Appetite Disorder (abnormal eating habits): 2 people, 6.25%
  9. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 2 people, 6.25%
  10. Sleep Disorder: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Reyvow and have Insomnia exacerbated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Reyvow:

Insomnia exacerbated treatments and more:

How severe was Insomnia exacerbated and when was it recovered:

Expand to all the drugs that have ingredients of lasmiditan succinate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Reyvow:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia exacerbated:

Browse all the conditions that are associated with Insomnia exacerbated:


How the study uses the data?

The study uses data from the FDA. It is based on lasmiditan succinate (the active ingredients of Reyvow) and Reyvow (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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