Rifaximin and Abdominal discomfort - a phase IV clinical study of FDA data

Summary:

Abdominal discomfort is reported as a side effect among people who take Rifaximin (rifaximin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tpn, and have Diarrhea.

The phase IV clinical study analyzes which people have Abdominal discomfort when taking Rifaximin. It is created by eHealthMe based on reports of 3,595 people who have side effects when taking Rifaximin from the FDA, and is updated regularly.

What is Rifaximin?

Rifaximin has active ingredients of rifaximin. eHealthMe is studying from 3,597 Rifaximin users. Check the latest studies of Rifaximin.

What is Abdominal discomfort?

Abdominal discomfort is found to be associated with 2,594 drugs and 3,519 conditions by eHealthMe. Check the latest studies of Abdominal discomfort.

On Aug, 05, 2026

3,595 people reported to have side effects when taking Rifaximin.
Among them, 28 people (0.78%) have Abdominal discomfort.

Could Rifaximin cause Abdominal discomfort?

Among these 28 people:

How long have people been on Rifaximin when they have Abdominal discomfort? *

What is the gender of people who have Abdominal discomfort when taking Rifaximin? *

female: 81.48 %
male: 18.52 %

What is the age of people who have Abdominal discomfort when taking Rifaximin? *

What are other drugs people take besides Rifaximin? *

What are other side effects people have besides Abdominal discomfort? *

Diarrhea: 14 people, 50.00%
Abdominal Distension: 12 people, 42.86%
Nausea (feeling of having an urge to vomit): 9 people, 32.14%
Flatulence (flatus expelled through the anus): 9 people, 32.14%
Nausea And Vomiting: 7 people, 25.00%
Abdominal Pain: 7 people, 25.00%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 25.00%
Injection Site Pain: 6 people, 21.43%
Headache (pain in head): 6 people, 21.43%
Weight Decreased: 6 people, 21.43%

What are the existing conditions these people have? *

Diarrhea: 7 people, 25.00%
Pain: 5 people, 17.86%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 17.86%
Vulvovaginal Candidiasis (vulvovaginal infection by fungi): 4 people, 14.29%
Urination - Painful: 4 people, 14.29%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 4 people, 14.29%
Perirectal Abscess: 4 people, 14.29%
Infection: 4 people, 14.29%
Thyroid Diseases: 3 people, 10.71%
Beta Haemolytic Streptococcal Infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue): 3 people, 10.71%

* Approximation only. Some reports may have incomplete information.

Do you take Rifaximin and have Abdominal discomfort?

- Check whether Abdominal discomfort is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rifaximin:

Rifaximin (3,597 reports)

Browse all side effects of Rifaximin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abdominal discomfort:

Abdominal discomfort (2,594 drugs)

Browse all the conditions that are associated with Abdominal discomfort:

Abdominal discomfort (3,519 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rifaximin (the active ingredients of Rifaximin) and Rifaximin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.