Thorazine and Ibuprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Thorazine (chlorpromazine hydrochloride) and Ibuprofen (ibuprofen). Common drug interactions include fall among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Thorazine and Ibuprofen. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Thorazine?

Thorazine has active ingredients of chlorpromazine hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 3,237 Thorazine users. Check the latest studies of Thorazine.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

On Aug, 05, 2026

100 people who take Thorazine and Ibuprofen together, and have interactions are studied.

Thorazine and Ibuprofen drug interactions.

What are the common drug interactions of Thorazine and Ibuprofen, by gender? *:

female:

Fall
Blood cholesterol increased
Anxiety
Death
Gait disturbance
Psychotic disorder
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Blood glucose increased
Depressed level of consciousness
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)

male:

Arthralgia (joint pain)
Type 2 diabetes mellitus
Abdominal pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cough
Foot fracture
Haematocrit decreased
Haemoglobin decreased
Hypertension (high blood pressure)
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)

What are the common drug interactions of Thorazine and Ibuprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood triglycerides increased
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Drug ineffective
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Impaired gastric emptying
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Obesity (having too much body fat)
Type 2 diabetes mellitus

20-29:

Acute sinusitis
Anxiety
Attention deficit/hyperactivity disorder
Blood cholesterol increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypertension (high blood pressure)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Migraine (headache)

30-39:

Arthralgia (joint pain)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 2 diabetes mellitus
Compulsive shopping
Eating disorder
Hospitalisation
Nephrolithiasis (calculi in the kidneys)
Weight increased
Anxiety
Blood cholesterol increased

40-49:

Type 2 diabetes mellitus
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Blood cholesterol increased
Death
Overdose
Fall
Agitation (state of anxiety or nervous excitement)
Blood glucose increased
Depressed level of consciousness
Diabetes mellitus inadequate control

50-59:

Peripheral swelling
Aggression
Agitation (state of anxiety or nervous excitement)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Balance disorder
Delusional disorder, unspecified type
Dizziness
Drooling (drop saliva uncontrollably from the mouth)
Dysarthria (speech disorder)
Fall

60+:

Drug hypersensitivity
Depression
Anaemia (lack of blood)
Atelectasis (partial or complete collapse of the lung)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dizziness
Gait disturbance
Hypertension (high blood pressure)
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

What are the existing conditions these people have? *

Depression: 23 people, 23.00%
Stress And Anxiety: 20 people, 20.00%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 18 people, 18.00%
Insomnia (sleeplessness): 11 people, 11.00%
Sleep Disorder: 9 people, 9.00%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 9 people, 9.00%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 8 people, 8.00%
Weight Loss: 6 people, 6.00%
Psychotic Disorder: 6 people, 6.00%
Nausea (feeling of having an urge to vomit): 5 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Thorazine and Ibuprofen?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously