Rybelsus and Sinusitis - a phase IV clinical study of FDA data

Summary:

Sinusitis is reported as a side effect among people who take Rybelsus (semaglutide), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Aspirin, and have Hidradenitis.

The phase IV clinical study analyzes which people have Sinusitis when taking Rybelsus. It is created by eHealthMe based on reports of 4,111 people who have side effects when taking Rybelsus from the FDA, and is updated regularly.

What is Rybelsus?

Rybelsus has active ingredients of semaglutide. eHealthMe is studying from 4,159 Rybelsus users. Check the latest studies of Rybelsus.

What is Sinusitis?

Sinusitis (inflammation of sinus) is found to be associated with 2,400 drugs and 2,727 conditions by eHealthMe. Check the latest studies of Sinusitis.

On Aug, 12, 2026

4,111 people reported to have side effects when taking Rybelsus.
Among them, 19 people (0.46%) have Sinusitis.

Among these 19 people:

How long have people been on Rybelsus when they have Sinusitis? *

What is the gender of people who have Sinusitis when taking Rybelsus? *

female: 84.62 %
male: 15.38 %

What is the age of people who have Sinusitis when taking Rybelsus? *

What are other drugs people take besides Rybelsus? *

Aspirin: 6 people, 31.58%
Ciprofloxacin Hydrochloride: 5 people, 26.32%
Albuterol Sulfate: 5 people, 26.32%
Zofran: 4 people, 21.05%
Ketoconazole: 4 people, 21.05%
Imitrex: 4 people, 21.05%
Hydroxyzine Hydrochloride: 4 people, 21.05%
Zithromax: 4 people, 21.05%
Hydroxyurea: 4 people, 21.05%
Finasteride: 4 people, 21.05%

What are other side effects people have besides Sinusitis? *

Nausea (feeling of having an urge to vomit): 8 people, 42.11%
Burning Sensation: 7 people, 36.84%
Nausea And Vomiting: 6 people, 31.58%
Fatigue (feeling of tiredness): 6 people, 31.58%
Dizziness: 5 people, 26.32%
Dry Mouth: 5 people, 26.32%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 5 people, 26.32%
Blood Thyroid Stimulating Hormone Decreased: 4 people, 21.05%
Hepatic Enzyme Increased: 4 people, 21.05%
Administration Site Pain: 4 people, 21.05%

What are the existing conditions these people have? *

Hidradenitis (chronic disease of a type of sweat gland): 5 people, 26.32%
Essential Thrombocythaemia (chronic blood cancer): 4 people, 21.05%
Type 2 Diabetes: 2 people, 10.53%
Immunodeficiency Common Variable: 2 people, 10.53%
Weight Increased: 1 person, 5.26%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 5.26%
Dry Eyes (lack of adequate tears): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Rybelsus and have Sinusitis?

- Check whether Sinusitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rybelsus:

Rybelsus (4,159 reports)

Sinusitis treatments and more:

Sinusitis (153,485 reports)

Browse all side effects of Rybelsus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinusitis:

Sinusitis (2,400 drugs)

Browse all the conditions that are associated with Sinusitis:

Sinusitis (2,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on semaglutide (the active ingredients of Rybelsus) and Rybelsus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.