Selexipag and Hypokalemia - a phase IV clinical study of FDA data

Summary:

Hypokalemia is reported as a side effect among people who take Selexipag (selexipag), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Macitentan, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Hypokalemia when taking Selexipag. It is created by eHealthMe based on reports of 2,593 people who have side effects when taking Selexipag from the FDA, and is updated regularly.

What is Selexipag?

Selexipag has active ingredients of selexipag. eHealthMe is studying from 2,593 Selexipag users. Check the latest studies of Selexipag.

What is Hypokalemia?

Hypokalemia (low potassium) is found to be associated with 2,093 drugs and 3,091 conditions by eHealthMe. Check the latest studies of Hypokalemia.



On Jul, 15, 2026

2,593 people reported to have side effects when taking Selexipag.
Among them, 18 people (0.69%) have Hypokalemia.

Could Selexipag cause Hypokalemia?

Among these 18 people:

How long have people been on Selexipag when they have Hypokalemia? *

  • < 1 month: 62.5 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 37.5 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypokalemia when taking Selexipag? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Hypokalemia when taking Selexipag? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 5.56 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.67 %
  • 50-59: 27.78 %
  • 60+: 50.0 %

What are other drugs people take besides Selexipag? *

  1. Adcirca: 8 people, 44.44%
  2. Macitentan: 8 people, 44.44%
  3. Pantoprazole: 6 people, 33.33%
  4. Bosentan: 4 people, 22.22%
  5. Spironolactone: 4 people, 22.22%
  6. Lasix: 3 people, 16.67%
  7. Ambrisentan: 3 people, 16.67%
  8. Torsemide: 3 people, 16.67%
  9. Nortriptyline Hydrochloride: 2 people, 11.11%
  10. Nifedipine: 2 people, 11.11%

What are other side effects people have besides Hypokalemia? *

  1. Nausea (feeling of having an urge to vomit): 8 people, 44.44%
  2. Headache (pain in head): 7 people, 38.89%
  3. Diarrhea: 6 people, 33.33%
  4. Anaemia (lack of blood): 5 people, 27.78%
  5. Nausea And Vomiting: 5 people, 27.78%
  6. Abdominal Pain: 5 people, 27.78%
  7. Abdominal Pain Upper: 5 people, 27.78%
  8. Pneumonia: 5 people, 27.78%
  9. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 4 people, 22.22%
  10. Hypotension (abnormally low blood pressure): 4 people, 22.22%

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 14 people, 77.78%
  2. High Blood Pressure: 7 people, 38.89%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 33.33%
  4. Cardiac Failure: 5 people, 27.78%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 22.22%
  6. Diabetes: 4 people, 22.22%
  7. Dyspnea (difficult or laboured breathing): 4 people, 22.22%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 22.22%
  9. Dyslipidaemia (abnormal amount of lipids): 3 people, 16.67%
  10. Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Selexipag and have Hypokalemia?

- Check whether Hypokalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Selexipag:

Hypokalemia treatments and more:

How severe was Hypokalemia and when was it recovered:

Expand to all the drugs that have ingredients of selexipag:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Selexipag:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypokalemia:

Browse all the conditions that are associated with Hypokalemia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on selexipag (the active ingredients of Selexipag) and Selexipag (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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