Seroquel and Ankylosing spondylitis - a phase IV clinical study of FDA data

Summary:

Ankylosing spondylitis is reported as a side effect among people who take Seroquel (quetiapine fumarate), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Lyrica, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Ankylosing spondylitis when taking Seroquel. It is created by eHealthMe based on reports of 113,615 people who have side effects when taking Seroquel from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

What is Ankylosing spondylitis?

Ankylosing spondylitis (type of arthritis affecting the spine) is found to be associated with 748 drugs and 1,048 conditions by eHealthMe. Check the latest studies of Ankylosing spondylitis.

On May, 04, 2026

113,615 people reported to have side effects when taking Seroquel.
Among them, 58 people (0.05%) have Ankylosing spondylitis.

Could Seroquel cause Ankylosing spondylitis?

Among these 58 people:

How long have people been on Seroquel when they have Ankylosing spondylitis? *

What is the gender of people who have Ankylosing spondylitis when taking Seroquel? *

female: 58.62 %
male: 41.38 %

What is the age of people who have Ankylosing spondylitis when taking Seroquel? *

What are other drugs people take besides Seroquel? *

What are other side effects people have besides Ankylosing spondylitis? *

Pain: 22 people, 37.93%
Joint Pain: 21 people, 36.21%
Cough: 12 people, 20.69%
Fibromyalgia (a long-term condition which causes pain all over the body): 12 people, 20.69%
Drug Ineffective: 11 people, 18.97%
Osteoporosis (bones weak and more likely to break): 11 people, 18.97%
Nasopharyngitis (inflammation of the nasopharynx): 11 people, 18.97%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 10 people, 17.24%
Back Pain: 10 people, 17.24%
The Flu (the flu is caused by an influenza virus): 10 people, 17.24%

What are the existing conditions these people have? *

Stress And Anxiety: 15 people, 25.86%
Fibromyalgia (a long-term condition which causes pain all over the body): 9 people, 15.52%
Osteoporosis (bones weak and more likely to break): 8 people, 13.79%
Stable Angina (a constant chest pain): 6 people, 10.34%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 10.34%
Inflammation: 6 people, 10.34%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 6 people, 10.34%
Pain: 5 people, 8.62%
Sleep Disorder: 5 people, 8.62%
High Blood Pressure: 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Seroquel and have Ankylosing spondylitis?

- Check whether Ankylosing spondylitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Seroquel:

Seroquel (120,285 reports)

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ankylosing spondylitis:

Ankylosing spondylitis (748 drugs)

Browse all the conditions that are associated with Ankylosing spondylitis:

Ankylosing spondylitis (1,048 conditions)

Related publications that referenced our studies

Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
Hung YM, Cheng CC, Wann SR, Lin SL, "Ankylosing spondylitis associated with pulmonary arterial hypertension", Internal Medicine, 2016 Jan .
Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
Hung YM, Cheng CC, Wann SR, Lin SL, "Ankylosing spondylitis associated with pulmonary arterial hypertension", Internal Medicine, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on quetiapine fumarate (the active ingredients of Seroquel) and Seroquel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.