Seroquel and Cholangitis - a phase IV clinical study of FDA data
Summary:
Cholangitis is reported as a side effect among people who take Seroquel (quetiapine fumarate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Depakote, and have Schizophrenia, paranoid type.
The phase IV clinical study analyzes which people have Cholangitis when taking Seroquel. It is created by eHealthMe based on reports of 113,615 people who have side effects when taking Seroquel from the FDA, and is updated regularly.
What is Seroquel?
Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.
What is Cholangitis?
Cholangitis (infection of the bile duct) is found to be associated with 654 drugs and 751 conditions by eHealthMe. Check the latest studies of Cholangitis.
113,615 people reported to have side effects when taking Seroquel.
Among them, 11 people (0.01%) have Cholangitis.

Among these 11 people:
How long have people been on Seroquel when they have Cholangitis? *
- < 1 month: 0.0 %
- 1 - 6 months: 75 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 25 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Cholangitis when taking Seroquel? *
- female: 60 %
- male: 40 %
What is the age of people who have Cholangitis when taking Seroquel? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 25 %
- 40-49: 0.0 %
- 50-59: 25 %
- 60+: 50 %
What are other drugs people take besides Seroquel? *
- Depakote: 4 people, 36.36%
- Vistaril: 3 people, 27.27%
- Zyprexa: 2 people, 18.18%
- Amiodarone Hydrochloride: 2 people, 18.18%
- Atorvastatin Calcium: 2 people, 18.18%
- Lipitor: 1 person, 9.09%
- Aricept: 1 person, 9.09%
- Atenolol: 1 person, 9.09%
- Byetta: 1 person, 9.09%
- Enoxaparin Sodium: 1 person, 9.09%
What are other side effects people have besides Cholangitis? *
- Gallstones (stone formation by bile component): 5 people, 45.45%
- Fever: 3 people, 27.27%
- Abdominal Pain: 2 people, 18.18%
- Hepatitis Toxic: 2 people, 18.18%
- Indigestion: 2 people, 18.18%
- Pancreatitis Acute (sudden inflammation of pancreas): 2 people, 18.18%
- Cholecystitis Chronic (long lasting infection of gallbladder): 1 person, 9.09%
- Death: 1 person, 9.09%
- Delirium (wild excitement): 1 person, 9.09%
- Blood Glucose Increased: 1 person, 9.09%
What are the existing conditions these people have? *
- Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 2 people, 18.18%
- Tachycardia Paroxysmal (a form of tachycardia which begins and ends in an acute (or paroxysmal) manner): 1 person, 9.09%
- Peripheral Vascular Disorder: 1 person, 9.09%
- Parkinson's Disease: 1 person, 9.09%
- Metastases To Lymph Nodes (cancer spreads to lymph node): 1 person, 9.09%
- Left Ventricular Failure (left ventricle fails to contract forcefully): 1 person, 9.09%
- Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 9.09%
- Hepatic Cancer Metastatic (liver cancer - metastatic): 1 person, 9.09%
- Dehydration (dryness resulting from the removal of water): 1 person, 9.09%
- Constipation: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Seroquel and have Cholangitis?
- Check whether Cholangitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Seroquel:
- Seroquel (120,285 reports)
Cholangitis treatments and more:
- Cholangitis (7,720 reports)
How severe was Cholangitis and when was it recovered:
Expand to all the drugs that have ingredients of quetiapine fumarate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Cholangitis:
- Cholangitis (654 drugs)
Browse all the conditions that are associated with Cholangitis:
- Cholangitis (751 conditions)
Related publications that referenced our studies
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on quetiapine fumarate (the active ingredients of Seroquel) and Seroquel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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