Seroquel and Executive dysfunction - a phase IV clinical study of FDA data

Summary:

Executive dysfunction is reported as a side effect among people who take Seroquel (quetiapine fumarate), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Adderall, and have Sleep disorder.

The phase IV clinical study analyzes which people have Executive dysfunction when taking Seroquel. It is created by eHealthMe based on reports of 113,615 people who have side effects when taking Seroquel from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,280 Seroquel users. Check the latest studies of Seroquel.

What is Executive dysfunction?

Executive dysfunction is found to be associated with 53 drugs and 129 conditions by eHealthMe. Check the latest studies of Executive dysfunction.

On Jan, 18, 2026

113,615 people reported to have side effects when taking Seroquel.
Among them, 11 people (0.01%) have Executive dysfunction.

Could Seroquel cause Executive dysfunction?

Among these 11 people:

How long have people been on Seroquel when they have Executive dysfunction? *

What is the gender of people who have Executive dysfunction when taking Seroquel? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Executive dysfunction when taking Seroquel? *

What are other drugs people take besides Seroquel? *

What are other side effects people have besides Executive dysfunction? *

Memory Loss: 7 people, 63.64%
Stress And Anxiety: 6 people, 54.55%
Agitation (state of anxiety or nervous excitement): 5 people, 45.45%
Sleep Disorder: 5 people, 45.45%
Nausea And Vomiting: 4 people, 36.36%
Feeling Abnormal: 4 people, 36.36%
Confusional State: 4 people, 36.36%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 27.27%
Dementia (madness): 3 people, 27.27%
Emotional Distress: 3 people, 27.27%

What are the existing conditions these people have? *

Sleep Disorder: 3 people, 27.27%
Vitamin B12 Decreased: 2 people, 18.18%
Parkinson's Disease: 2 people, 18.18%
Affective Disorder (mental disorder): 2 people, 18.18%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 18.18%
Osteoporosis (bones weak and more likely to break): 2 people, 18.18%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 9.09%
Pain: 1 person, 9.09%
Stress And Anxiety: 1 person, 9.09%
High Blood Pressure: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Seroquel and have Executive dysfunction?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Seroquel:

Seroquel (120,280 reports)

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Executive dysfunction:

Executive dysfunction (53 drugs)

Browse all the conditions that are associated with Executive dysfunction:

Executive dysfunction (129 conditions)

Drugs similar to Seroquel and Executive dysfunction :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on quetiapine fumarate (the active ingredients of Seroquel) and Seroquel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.