Serzone and Bone density decreased - a phase IV clinical study of FDA data

Summary:

Bone density decreased is reported as a side effect among people who take Serzone (nefazodone hydrochloride), especially for people who are female, 50-59 old, also take Zoloft, and have Menopause.

The phase IV clinical study analyzes which people have Bone density decreased when taking Serzone. It is created by eHealthMe based on reports of 7,594 people who have side effects when taking Serzone from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Bone density decreased?

Bone density decreased is found to be associated with 1,126 drugs and 945 conditions by eHealthMe. Check the latest studies of Bone density decreased.



On Jul, 11, 2026

7,594 people reported to have side effects when taking Serzone.
Among them, 12 people (0.16%) have Bone density decreased.

Could Serzone cause Bone density decreased?

Among these 12 people:

What is the gender of people who have Bone density decreased when taking Serzone? *

  • female: 58.33 %
  • male: 41.67 %

What is the age of people who have Bone density decreased when taking Serzone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 72.73 %
  • 60+: 27.27 %

What are other drugs people take besides Serzone? *

  1. Wellbutrin: 9 people, 75.00%
  2. Zoloft: 9 people, 75.00%
  3. Toprol-Xl: 6 people, 50.00%
  4. Lisinopril: 6 people, 50.00%
  5. Prevpac: 6 people, 50.00%
  6. Premarin: 6 people, 50.00%
  7. Prozac: 6 people, 50.00%
  8. Percocet: 6 people, 50.00%
  9. Remeron: 6 people, 50.00%
  10. Nicotrol: 6 people, 50.00%

What are other side effects people have besides Bone density decreased? *

  1. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 6 people, 50.00%
  2. Impaired Fasting Glucose: 6 people, 50.00%
  3. Hepatitis C: 6 people, 50.00%
  4. Hepatomegaly (abnormal enlargement of the liver): 6 people, 50.00%
  5. High Blood Cholesterol: 6 people, 50.00%
  6. High Blood Pressure: 6 people, 50.00%
  7. Hot Flush (sudden feelings of heat): 6 people, 50.00%
  8. Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 50.00%
  9. Hypokalemia (low potassium): 6 people, 50.00%
  10. Influenza Like Illness: 6 people, 50.00%

What are the existing conditions these people have? *

  1. Sleep Disorder: 6 people, 50.00%
  2. Menopause (end of monthly cycles in women): 6 people, 50.00%
  3. Hiv Infection: 5 people, 41.67%
  4. Viral Infection: 3 people, 25.00%
  5. Urinary Retention (the inability to completely or partially empty the bladder): 3 people, 25.00%
  6. Pain: 3 people, 25.00%
  7. Insomnia (sleeplessness): 3 people, 25.00%
  8. Indigestion: 3 people, 25.00%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 25.00%
  10. Hypersensitivity: 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Serzone and have Bone density decreased?

- Check whether Bone density decreased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Serzone:

Bone density decreased treatments and more:

How severe was Bone density decreased and when was it recovered:

Expand to all the drugs that have ingredients of nefazodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Serzone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone density decreased:

Browse all the conditions that are associated with Bone density decreased:


How the study uses the data?

The study uses data from the FDA. It is based on nefazodone hydrochloride (the active ingredients of Serzone) and Serzone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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