Simponi and Mean cell volume decreased - a phase IV clinical study of FDA data

Summary:

Mean cell volume decreased is reported as a side effect among people who take Simponi (golimumab), especially for people who are female, 20-29 old, have been taking the drug for 2 - 5 years also take Humira, and have Juvenile rheumatoid arthritis.

The phase IV clinical study analyzes which people have Mean cell volume decreased when taking Simponi. It is created by eHealthMe based on reports of 86,103 people who have side effects when taking Simponi from the FDA, and is updated regularly.

What is Simponi?

Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.

What is Mean cell volume decreased?

Mean cell volume decreased (less of the average red blood cell volume) is found to be associated with 320 drugs and 427 conditions by eHealthMe. Check the latest studies of Mean cell volume decreased.

On Jul, 27, 2026

86,103 people reported to have side effects when taking Simponi.
Among them, 44 people (0.05%) have Mean cell volume decreased.

Could Simponi cause Mean cell volume decreased?

Among these 44 people:

How long have people been on Simponi when they have Mean cell volume decreased? *

What is the gender of people who have Mean cell volume decreased when taking Simponi? *

female: 100 %
male: 0.0 %

What is the age of people who have Mean cell volume decreased when taking Simponi? *

What are other drugs people take besides Simponi? *

What are other side effects people have besides Mean cell volume decreased? *

Mean Cell Haemoglobin Decreased (less than normal haemoglobin per red blood cell in a sample of blood): 43 people, 97.73%
Platelet Count Increased: 43 people, 97.73%
C-Reactive Protein Increased: 41 people, 93.18%
Drug Ineffective: 40 people, 90.91%
Hand Deformity: 39 people, 88.64%
Pain: 39 people, 88.64%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 39 people, 88.64%
Therapeutic Response Decreased (less preventive response): 38 people, 86.36%
Hypersensitivity: 38 people, 86.36%
Mean Platelet Volume Decreased (less than normal average size of platelet cells in blood): 37 people, 84.09%

What are the existing conditions these people have? *

Polyarthritis (arthritis which involves 5 or more joints simultaneously): 37 people, 84.09%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 37 people, 84.09%

* Approximation only. Some reports may have incomplete information.

Do you take Simponi and have Mean cell volume decreased?

- Check whether Mean cell volume decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simponi:

Simponi (86,328 reports)

Browse all side effects of Simponi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mean cell volume decreased:

Mean cell volume decreased (320 drugs)

Browse all the conditions that are associated with Mean cell volume decreased:

Mean cell volume decreased (427 conditions)

Related publications that referenced our studies

Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .

How the study uses the data?

The study uses data from the FDA. It is based on golimumab (the active ingredients of Simponi) and Simponi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.