Simvastatin and Blood alkaline phosphatase abnormal - a phase IV clinical study of FDA data

Summary:

Blood alkaline phosphatase abnormal is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Tracleer, and have Hyperuricaemia.

The phase IV clinical study analyzes which people have Blood alkaline phosphatase abnormal when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Blood alkaline phosphatase abnormal?

Blood alkaline phosphatase abnormal is found to be associated with 173 drugs and 326 conditions by eHealthMe. Check the latest studies of Blood alkaline phosphatase abnormal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 29, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 22 people (0.01%) have Blood alkaline phosphatase abnormal.

Could Simvastatin cause Blood alkaline phosphatase abnormal?

Among these 22 people:

How long have people been on Simvastatin when they have Blood alkaline phosphatase abnormal? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 66.67 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Blood alkaline phosphatase abnormal when taking Simvastatin? *

  • female: 36.36 %
  • male: 63.64 %

What is the age of people who have Blood alkaline phosphatase abnormal when taking Simvastatin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 26.32 %
  • 60+: 73.68 %

What are other drugs people take besides Simvastatin? *

  1. Tracleer: 6 people, 27.27%
  2. Ocaliva: 4 people, 18.18%
  3. Vitamin B6: 3 people, 13.64%
  4. Benlysta: 3 people, 13.64%
  5. Bactrim Ds: 3 people, 13.64%
  6. Actigall: 3 people, 13.64%
  7. Vitamin C: 3 people, 13.64%
  8. Metformin: 3 people, 13.64%
  9. Amisulpride: 2 people, 9.09%
  10. Tadalafil: 2 people, 9.09%

What are other side effects people have besides Blood alkaline phosphatase abnormal? *

  1. Aspartate Aminotransferase Increased: 9 people, 40.91%
  2. Nausea And Vomiting: 9 people, 40.91%
  3. Nausea (feeling of having an urge to vomit): 9 people, 40.91%
  4. Alanine Aminotransferase Increased: 8 people, 36.36%
  5. Abdominal Pain: 8 people, 36.36%
  6. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 7 people, 31.82%
  7. Blood Bilirubin Increased: 7 people, 31.82%
  8. Lipase Increased: 6 people, 27.27%
  9. Alanine Aminotransferase Abnormal: 6 people, 27.27%
  10. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 27.27%

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 27.27%
  2. Cardiac Failure: 6 people, 27.27%
  3. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 6 people, 27.27%
  4. Diabetes: 6 people, 27.27%
  5. Pulmonary Hypertension (increase in blood pressure in the lung artery): 6 people, 27.27%
  6. Gastritis (inflammation of stomach): 6 people, 27.27%
  7. Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 27.27%
  8. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 6 people, 27.27%
  9. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 13.64%
  10. Skin Ulcer: 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Blood alkaline phosphatase abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Blood alkaline phosphatase abnormal treatments and more:

How severe was Blood alkaline phosphatase abnormal and when was it recovered:

Expand to all the drugs that have ingredients of simvastatin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood alkaline phosphatase abnormal:

Browse all the conditions that are associated with Blood alkaline phosphatase abnormal:


How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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