Simvastatin and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Mcp, and have Pain.

The phase IV clinical study analyzes which people have Cachexia when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,959 Simvastatin users. Check the latest studies of Simvastatin.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 729 drugs and 1,194 conditions by eHealthMe. Check the latest studies of Cachexia.

On Nov, 05, 2025

249,370 people reported to have side effects when taking Simvastatin.
Among them, 123 people (0.05%) have Cachexia.

Among these 123 people:

How long have people been on Simvastatin when they have Cachexia? *

What is the gender of people who have Cachexia when taking Simvastatin? *

female: 59.5 %
male: 40.5 %

What is the age of people who have Cachexia when taking Simvastatin? *

What are other drugs people take besides Simvastatin? *

What are other side effects people have besides Cachexia? *

Weight Decreased: 44 people, 35.77%
Weakness: 44 people, 35.77%
Dyspnea (difficult or laboured breathing): 41 people, 33.33%
Fatigue (feeling of tiredness): 40 people, 32.52%
Pneumonia: 36 people, 29.27%
General Physical Health Deterioration (weak health status): 35 people, 28.46%
Anaemia (lack of blood): 34 people, 27.64%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 33 people, 26.83%
Dizziness: 28 people, 22.76%
Fever: 26 people, 21.14%

What are the existing conditions these people have? *

Pain: 15 people, 12.20%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 11 people, 8.94%
Nausea (feeling of having an urge to vomit): 11 people, 8.94%
Depression: 11 people, 8.94%
Constipation: 10 people, 8.13%
Diarrhea: 10 people, 8.13%
C-Reactive Protein Increased: 9 people, 7.32%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 9 people, 7.32%
Tremor (trembling or shaking movements in one or more parts of your body): 9 people, 7.32%
Gastritis - Chronic (long lasting inflammation of stomach): 9 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,959 reports)

Cachexia treatments and more:

Cachexia (7,763 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Cachexia:

Browse all the drugs that are associated with Cachexia:

Cachexia (729 drugs)

Common conditions associated with Cachexia:

Hiv infection: 326 reports
Human immunodeficiency virus infection: 320 reports
Hiv test: 302 reports
Pain exacerbated: 296 reports
Alternative medicine - pain relief: 283 reports
Hypertension aggravated: 218 reports
High blood pressure: 212 reports
Metastatic renal cell carcinoma: 196 reports
Acupuncture and pain: 193 reports
Rheumatoid arthritis: 177 reports

Browse all the conditions that are associated with Cachexia:

Cachexia (1,194 conditions)

Drugs similar to Simvastatin and Cachexia :

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.