Simvastatin and Chronic thyroiditis - a phase IV clinical study of FDA data

Summary:

Chronic thyroiditis is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, also take Byetta, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Chronic thyroiditis when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,967 Simvastatin users. Check the latest studies of Simvastatin.

What is Chronic thyroiditis?

Chronic thyroiditis (long lasting inflammation of thyroid gland) is found to be associated with 458 drugs and 1,084 conditions by eHealthMe. Check the latest studies of Chronic thyroiditis.



On May, 03, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 26 people (0.01%) have Chronic thyroiditis.

Could Simvastatin cause Chronic thyroiditis?

Among these 26 people:

What is the gender of people who have Chronic thyroiditis when taking Simvastatin? *

  • female: 69.23 %
  • male: 30.77 %

What is the age of people who have Chronic thyroiditis when taking Simvastatin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4.35 %
  • 40-49: 8.7 %
  • 50-59: 17.39 %
  • 60+: 69.57 %

What are other drugs people take besides Simvastatin? *

  1. Byetta: 7 people, 26.92%
  2. Folic Acid: 6 people, 23.08%
  3. Lovaza: 5 people, 19.23%
  4. Aspirin: 5 people, 19.23%
  5. Lisinopril: 4 people, 15.38%
  6. Vitamin D3: 4 people, 15.38%
  7. Tizanidine Hydrochloride: 3 people, 11.54%
  8. Methotrexate: 3 people, 11.54%
  9. Losartan Potassium: 3 people, 11.54%
  10. Ranolazine: 3 people, 11.54%

What are other side effects people have besides Chronic thyroiditis? *

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 19.23%
  2. Papillary Thyroid Cancer: 5 people, 19.23%
  3. Post Procedural Hypothyroidism: 4 people, 15.38%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 15.38%
  5. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 4 people, 15.38%
  6. Fatigue (feeling of tiredness): 4 people, 15.38%
  7. Sinusitis (inflammation of sinus): 3 people, 11.54%
  8. Serratia Infection (bacterial infection): 3 people, 11.54%
  9. Hypotension (abnormally low blood pressure): 3 people, 11.54%
  10. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 3 people, 11.54%

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 5 people, 19.23%
  2. Immunodeficiency Common Variable: 3 people, 11.54%
  3. Sleep Disorder: 2 people, 7.69%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.69%
  5. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 2 people, 7.69%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 7.69%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
  8. Back Pain: 2 people, 7.69%
  9. Urinary Tract Infection: 1 person, 3.85%
  10. Neuralgia (pain in one or more nerves): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Chronic thyroiditis?

- Check whether Chronic thyroiditis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Chronic thyroiditis treatments and more:

How severe was Chronic thyroiditis and when was it recovered:

Expand to all the drugs that have ingredients of simvastatin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chronic thyroiditis:

Browse all the conditions that are associated with Chronic thyroiditis:


How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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