Simvastatin and High blood cholesterol - a phase IV clinical study of FDA data

Summary:

High blood cholesterol is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Aspirin, and have Diabetes.

The phase IV clinical study analyzes which people have High blood cholesterol when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

What is High blood cholesterol?

High blood cholesterol is found to be associated with 2,281 drugs and 3,556 conditions by eHealthMe. Check the latest studies of High blood cholesterol.

On May, 14, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 2,851 people (1.14%) have High blood cholesterol.

Could Simvastatin cause High blood cholesterol?

Among these 2,851 people:

How long have people been on Simvastatin when they have High blood cholesterol? *

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What is the gender of people who have High blood cholesterol when taking Simvastatin? *

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What is the age of people who have High blood cholesterol when taking Simvastatin? *

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* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have High blood cholesterol?

- Check whether High blood cholesterol is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,969 reports)

High blood cholesterol treatments and more:

High blood cholesterol (478,575 reports)

How severe was High blood cholesterol and when was it recovered:

High blood cholesterol in Simvastatin

Expand to all the drugs that have ingredients of simvastatin:

High blood cholesterol and drugs with ingredients of simvastatin (5,007 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with High blood cholesterol:

High blood cholesterol (2,281 drugs)

Browse all the conditions that are associated with High blood cholesterol:

High blood cholesterol (3,556 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.