Simvastatin and Ibs - a phase IV clinical study of FDA data

Summary:

Ibs is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prevacid, and have Depression.

The phase IV clinical study analyzes which people have Ibs when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,964 Simvastatin users. Check the latest studies of Simvastatin.

What is Ibs?

Ibs (irritable bowel syndrome -chronic abdominal pain, discomfort, bloating) is found to be associated with 1,293 drugs and 2,077 conditions by eHealthMe. Check the latest studies of Ibs.

On Jan, 04, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 435 people (0.17%) have Ibs.

Among these 435 people:

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Ibs?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,964 reports)

Ibs treatments and more:

Ibs (49,234 reports)

How severe was Ibs and when was it recovered:

Ibs in Simvastatin

Expand to all the drugs that have ingredients of simvastatin:

Ibs and drugs with ingredients of simvastatin (636 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Simvastatin side effects:

Simvastatin side effect: Dyspnea (difficult or laboured breathing) (13,440 reports)
Simvastatin side effect: Dizziness (12,386 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Ibs:

Accutane side effect: Ibs (4,852 reports)
Prednisone side effect: Ibs (4,602 reports)
Methotrexate side effect: Ibs (4,404 reports)
Enbrel side effect: Ibs (3,973 reports)
Humira side effect: Ibs (3,774 reports)
Cimzia side effect: Ibs (3,643 reports)
Simponi side effect: Ibs (3,577 reports)
Actemra side effect: Ibs (3,567 reports)
Profen side effect: Ibs (3,554 reports)
Ibuprofen side effect: Ibs (3,553 reports)

Browse all the drugs that are associated with Ibs:

Ibs (1,293 drugs)

Common conditions associated with Ibs:

Ra: 4,917 reports
Acne: 3,228 reports
Acne vulgaris: 3,213 reports
Hypertension aggravated: 1,944 reports
Psoriatic arthropathy: 1,455 reports
Plaque psoriasis: 1,104 reports
Osteoporosis: 1,056 reports
Thin bones: 1,037 reports
Pain exacerbated: 1,027 reports
Alternative medicine - pain relief: 1,021 reports

Browse all the conditions that are associated with Ibs:

Ibs (2,077 conditions)

Drugs similar to Simvastatin and Ibs :

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.