Simvastatin and Light sensitivity - a phase IV clinical study of FDA data

Summary:

Light sensitivity is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have Neurotrophic keratopathy.

The phase IV clinical study analyzes which people have Light sensitivity when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,961 Simvastatin users. Check the latest studies of Simvastatin.

What is Light sensitivity?

Light sensitivity is found to be associated with 2,059 drugs and 1,821 conditions by eHealthMe. Check the latest studies of Light sensitivity.



On Dec, 06, 2025

249,370 people reported to have side effects when taking Simvastatin.
Among them, 432 people (0.17%) have Light sensitivity.

Could Simvastatin cause Light sensitivity?

Among these 432 people:

How long have people been on Simvastatin when they have Light sensitivity? *

  • < 1 month: 76.92 %
  • 1 - 6 months: 7.69 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 7.69 %
  • 5 - 10 years: 7.69 %
  • 10+ years: 0.0 %

What is the gender of people who have Light sensitivity when taking Simvastatin? *

  • female: 63.68 %
  • male: 36.32 %

What is the age of people who have Light sensitivity when taking Simvastatin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.54 %
  • 20-29: 1.08 %
  • 30-39: 8.65 %
  • 40-49: 9.73 %
  • 50-59: 19.46 %
  • 60+: 60.54 %

What are other drugs people take besides Simvastatin? *

  1. Aspirin: 200 people, 46.30%
  2. Hydrochlorothiazide: 194 people, 44.91%
  3. Nitroglycerin: 188 people, 43.52%
  4. Docetaxel: 187 people, 43.29%
  5. Norfloxacin: 187 people, 43.29%
  6. Ezetimibe: 187 people, 43.29%
  7. Acetaminophen: 187 people, 43.29%
  8. Celecoxib: 186 people, 43.06%
  9. Pentoxifylline: 186 people, 43.06%
  10. Letrozole: 186 people, 43.06%

What are other side effects people have besides Light sensitivity? *

  1. Headache (pain in head): 279 people, 64.58%
  2. Fatigue (feeling of tiredness): 246 people, 56.94%
  3. Eye Pain: 237 people, 54.86%
  4. Weakness: 233 people, 53.94%
  5. Dizziness: 228 people, 52.78%
  6. Vision Blurred: 225 people, 52.08%
  7. Joint Pain: 210 people, 48.61%
  8. Nausea And Vomiting: 201 people, 46.53%
  9. Nausea (feeling of having an urge to vomit): 201 people, 46.53%
  10. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 200 people, 46.30%

What are the existing conditions these people have? *

  1. Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 20 people, 4.63%
  2. Depression: 14 people, 3.24%
  3. Blood Pressure Abnormal: 14 people, 3.24%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 12 people, 2.78%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 12 people, 2.78%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 2.55%
  7. Pain: 11 people, 2.55%
  8. Sleep Disorder: 10 people, 2.31%
  9. Dry Eyes (lack of adequate tears): 9 people, 2.08%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 2.08%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Light sensitivity?

- Check whether Light sensitivity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Light sensitivity treatments and more:

How severe was Light sensitivity and when was it recovered:

Expand to all the drugs that have ingredients of simvastatin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Simvastatin side effects:

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Light sensitivity:

Browse all the drugs that are associated with Light sensitivity:

Common conditions associated with Light sensitivity:

Browse all the conditions that are associated with Light sensitivity:

Drugs similar to Simvastatin and Light sensitivity :


How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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