Simvastatin and Lightheadedness - a phase IV clinical study of FDA data

Summary:

Lightheadedness is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Lightheadedness when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,959 Simvastatin users. Check the latest studies of Simvastatin.

What is Lightheadedness?

Lightheadedness (a common and often unpleasant sensation of dizziness and/or feeling that one may be about to faint) is found to be associated with 3,977 drugs and 5,752 conditions by eHealthMe. Check the latest studies of Lightheadedness.

On Sep, 12, 2025

249,370 people reported to have side effects when taking Simvastatin.
Among them, 12,386 people (4.97%) have Lightheadedness.

Could Simvastatin cause Lightheadedness?

Among these 12,386 people:

How long have people been on Simvastatin when they have Lightheadedness? *

What is the gender of people who have Lightheadedness when taking Simvastatin? *

female: 53.98 %
male: 46.02 %

What is the age of people who have Lightheadedness when taking Simvastatin? *

What are other drugs people take besides Simvastatin? *

What are other side effects people have besides Lightheadedness? *

Nausea (feeling of having an urge to vomit): 3,044 people, 24.58%
Fatigue (feeling of tiredness): 2,992 people, 24.16%
Weakness: 2,665 people, 21.52%
Headache (pain in head): 2,534 people, 20.46%
Dyspnea (difficult or laboured breathing): 2,319 people, 18.72%
Diarrhea: 1,882 people, 15.19%
Fall: 1,839 people, 14.85%
Malaise (a feeling of general discomfort or uneasiness): 1,803 people, 14.56%
Nausea And Vomiting: 1,786 people, 14.42%
Pain: 1,507 people, 12.17%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 693 people, 5.60%
Pain: 620 people, 5.01%
Diabetes: 608 people, 4.91%
Depression: 600 people, 4.84%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 485 people, 3.92%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 433 people, 3.50%
Type 2 Diabetes: 414 people, 3.34%
Blood Pressure Abnormal: 391 people, 3.16%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 369 people, 2.98%
Ill-Defined Disorder: 353 people, 2.85%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Lightheadedness?

- Check whether Lightheadedness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,959 reports)

Lightheadedness treatments and more:

Lightheadedness (613,935 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Lightheadedness:

Browse all the drugs that are associated with Lightheadedness:

Lightheadedness (3,977 drugs)

Common conditions associated with Lightheadedness:

Browse all the conditions that are associated with Lightheadedness:

Lightheadedness (5,752 conditions)

Drugs similar to Simvastatin and Lightheadedness :

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.