Simvastatin and Nitrite urine present - a phase IV clinical study of FDA data

Summary:

Nitrite urine present is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, also take Metformin, and have Constipation.

The phase IV clinical study analyzes which people have Nitrite urine present when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Nitrite urine present?

Nitrite urine present (nitrite in urine) is found to be associated with 86 drugs and 204 conditions by eHealthMe. Check the latest studies of Nitrite urine present.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 13 people (0.01%) have Nitrite urine present.

Could Simvastatin cause Nitrite urine present?

Among these 13 people:

What is the gender of people who have Nitrite urine present when taking Simvastatin? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Nitrite urine present when taking Simvastatin? *

What are other drugs people take besides Simvastatin? *

What are other side effects people have besides Nitrite urine present? *

Abdominal Symptom: 7 people, 53.85%
Urinary Tract Infection: 5 people, 38.46%
Fever: 3 people, 23.08%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 15.38%
Blood Alkaline Phosphatase Increased: 2 people, 15.38%
C-Reactive Protein Increased: 2 people, 15.38%
Glycosylated Haemoglobin Increased: 2 people, 15.38%
Hypotension (abnormally low blood pressure): 2 people, 15.38%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 15.38%
Blood Glucose Increased: 2 people, 15.38%

What are the existing conditions these people have? *

Constipation: 7 people, 53.85%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.69%
Type 2 Diabetes: 1 person, 7.69%
Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 1 person, 7.69%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 7.69%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 7.69%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.69%
Hodgkin's Lymphoma (cancer originating from white blood cells): 1 person, 7.69%
Diabetes: 1 person, 7.69%
Cardiac Failure: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Nitrite urine present?

- Check whether Nitrite urine present is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,970 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nitrite urine present:

Nitrite urine present (86 drugs)

Browse all the conditions that are associated with Nitrite urine present:

Nitrite urine present (204 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.