Simvastatin and Nodal arrhythmia - a phase IV clinical study of FDA data

Summary:

Nodal arrhythmia is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Aspirin, and have Nausea.

The phase IV clinical study analyzes which people have Nodal arrhythmia when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Nodal arrhythmia?

Nodal arrhythmia (an irregular heart beat originating from within the atrioventricular node) is found to be associated with 204 drugs and 278 conditions by eHealthMe. Check the latest studies of Nodal arrhythmia.

On Aug, 05, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 47 people (0.02%) have Nodal arrhythmia.

Could Simvastatin cause Nodal arrhythmia?

Among these 47 people:

How long have people been on Simvastatin when they have Nodal arrhythmia? *

What is the gender of people who have Nodal arrhythmia when taking Simvastatin? *

female: 23.4 %
male: 76.6 %

What is the age of people who have Nodal arrhythmia when taking Simvastatin? *

What are other drugs people take besides Simvastatin? *

What are other side effects people have besides Nodal arrhythmia? *

Hyperkalemia (damage to or disease of the kidney): 13 people, 27.66%
Acute Kidney Failure: 13 people, 27.66%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 13 people, 27.66%
Pleural Effusion (water on the lungs): 7 people, 14.89%
Pneumonia: 7 people, 14.89%
Cardiac Arrest: 6 people, 12.77%
Arrhythmia Supraventricular (irregular heartbeat supraventricular origin): 6 people, 12.77%
Vitreous Haemorrhage (intraocular (inside the eye) bleeding): 6 people, 12.77%
Chest Pain: 6 people, 12.77%
Pain In Extremity: 6 people, 12.77%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 7 people, 14.89%
Burkitt Lymphoma (cancer of the lymphatic system): 6 people, 12.77%
Lung Cancer - Non-Small Cell (lung cancer): 6 people, 12.77%
Hypersensitivity: 6 people, 12.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.77%
Nausea And Vomiting: 4 people, 8.51%
Actinic Keratosis (skin disease due to sun exposure): 3 people, 6.38%
Erection Problems: 3 people, 6.38%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 6.38%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 4.26%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Nodal arrhythmia?

- Check whether Nodal arrhythmia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,970 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nodal arrhythmia:

Nodal arrhythmia (204 drugs)

Browse all the conditions that are associated with Nodal arrhythmia:

Nodal arrhythmia (278 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.