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Simvastatin and Oral lichen planus - a phase IV clinical study of FDA data

Summary:

Oral lichen planus is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, also take Prolia, and have Osteoporosis.

The phase IV clinical study analyzes which people have Oral lichen planus when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Oral lichen planus?

Oral lichen planus (a chronic inflammatory disease that causes bilateral white striations, papules, or plaques on the buccal mucosa) is found to be associated with 66 drugs and 220 conditions by eHealthMe. Check the latest studies of Oral lichen planus.

On Aug, 12, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 14 people (0.01%) have Oral lichen planus.

Could Simvastatin cause Oral lichen planus?

Among these 14 people:

What is the gender of people who have Oral lichen planus when taking Simvastatin? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Oral lichen planus when taking Simvastatin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 9.09 %
  • 60+: 90.91 %

What are other drugs people take besides Simvastatin? *

  1. Prolia: 10 people, 71.43%
  2. Zetia: 2 people, 14.29%
  3. Detrol La: 2 people, 14.29%
  4. Fluorouracil: 2 people, 14.29%
  5. Flonase Allergy Relief: 2 people, 14.29%
  6. Fish Oil: 2 people, 14.29%
  7. Erythromycin: 2 people, 14.29%
  8. Enstilar: 2 people, 14.29%
  9. Dexamethasone: 2 people, 14.29%
  10. Clonidine Hydrochloride: 2 people, 14.29%

What are other side effects people have besides Oral lichen planus? *

  1. Weight Decreased: 2 people, 14.29%
  2. Fall: 2 people, 14.29%
  3. Abnormal Behavior: 2 people, 14.29%
  4. Concussion (short loss of normal brain function in response to a head injury): 2 people, 14.29%
  5. Depression: 2 people, 14.29%
  6. Diabetes: 2 people, 14.29%
  7. Drowsiness: 2 people, 14.29%
  8. Face Injury: 2 people, 14.29%
  9. Abdominal Pain Upper: 2 people, 14.29%
  10. Snoring: 2 people, 14.29%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 10 people, 71.43%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 14.29%
  3. Drowsiness: 2 people, 14.29%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Oral lichen planus?

- Check whether Oral lichen planus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Oral lichen planus treatments and more:

How severe was Oral lichen planus and when was it recovered:

Expand to all the drugs that have ingredients of simvastatin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oral lichen planus:

Browse all the conditions that are associated with Oral lichen planus:

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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