Simvastatin and Oral mucosal eruption - a phase IV clinical study of FDA data

Summary:

Oral mucosal eruption is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Multihance, and have Vulvovaginal dryness.

The phase IV clinical study analyzes which people have Oral mucosal eruption when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

What is Oral mucosal eruption?

Oral mucosal eruption (a sudden appearing of rash on mucous membrane of mouth) is found to be associated with 174 drugs and 324 conditions by eHealthMe. Check the latest studies of Oral mucosal eruption.

On Jul, 04, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 20 people (0.01%) have Oral mucosal eruption.

Could Simvastatin cause Oral mucosal eruption?

Among these 20 people:

How long have people been on Simvastatin when they have Oral mucosal eruption? *

What is the gender of people who have Oral mucosal eruption when taking Simvastatin? *

female: 78.95 %
male: 21.05 %

What is the age of people who have Oral mucosal eruption when taking Simvastatin? *

What are other drugs people take besides Simvastatin? *

What are other side effects people have besides Oral mucosal eruption? *

Rashes (redness): 10 people, 50.00%
Nausea (feeling of having an urge to vomit): 5 people, 25.00%
Pain: 5 people, 25.00%
Dehydration (dryness resulting from the removal of water): 5 people, 25.00%
Swallowing Difficulty: 5 people, 25.00%
Hypersensitivity: 4 people, 20.00%
Skin Discoloration: 4 people, 20.00%
Weight Decreased: 4 people, 20.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 20.00%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 4 people, 20.00%

What are the existing conditions these people have? *

Vulvovaginal Dryness: 4 people, 20.00%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 15.00%
Diabetes: 3 people, 15.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 10.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 10.00%
Pemphigoid (tense blisters on the skin): 2 people, 10.00%
Pain: 2 people, 10.00%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 2 people, 10.00%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Oral mucosal eruption?

- Check whether Oral mucosal eruption is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,969 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oral mucosal eruption:

Oral mucosal eruption (174 drugs)

Browse all the conditions that are associated with Oral mucosal eruption:

Oral mucosal eruption (324 conditions)

Related publications that referenced our studies

Sahoo HB, Rath B, Behera JP, Moharana CS, "Cefuroxime axetil associated oral eruption: A case report", Apollo Medicine, 2016 Jun .
Sahoo HB, Rath B, Behera JP, Moharana CS, "Cefuroxime axetil associated oral eruption: A case report", Apollo Medicine, 2016 Jun .

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.