Simvastatin and Respiratory fatigue - a phase IV clinical study of FDA data

Summary:

Respiratory fatigue is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Esbriet, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Respiratory fatigue when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Respiratory fatigue?

Respiratory fatigue (a loss of the capability of the respiratory muscle) is found to be associated with 30 drugs and 113 conditions by eHealthMe. Check the latest studies of Respiratory fatigue.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 13 people (0.01%) have Respiratory fatigue.

Could Simvastatin cause Respiratory fatigue?

Among these 13 people:

How long have people been on Simvastatin when they have Respiratory fatigue? *

What is the gender of people who have Respiratory fatigue when taking Simvastatin? *

female: 15.38 %
male: 84.62 %

What is the age of people who have Respiratory fatigue when taking Simvastatin? *

What are other drugs people take besides Simvastatin? *

Rosuvastatin Calcium: 1 person, 7.69%
Esbriet: 1 person, 7.69%

What are other side effects people have besides Respiratory fatigue? *

Oedema (fluid collection in tissue): 6 people, 46.15%
Muscle Spasms (muscle contraction): 6 people, 46.15%
Dyspnea (difficult or laboured breathing): 3 people, 23.08%
Oedema Peripheral (superficial swelling): 3 people, 23.08%
Infection: 2 people, 15.38%
Tumor Lysis Syndrome: 2 people, 15.38%
Atypical Pneumonia (acute respiratory disease marked by high fever and coughing): 2 people, 15.38%
Blood Phosphorus Increased: 2 people, 15.38%
Chills (felling of cold): 2 people, 15.38%
Crepitations (noises are produced by the rubbing of parts one against the other): 2 people, 15.38%

What are the existing conditions these people have? *

Muscle Spasms (muscle contraction): 2 people, 15.38%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 15.38%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 15.38%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 7.69%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.69%
Enlarged Prostate: 1 person, 7.69%
B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Respiratory fatigue?

- Check whether Respiratory fatigue is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,970 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Respiratory fatigue:

Respiratory fatigue (30 drugs)

Browse all the conditions that are associated with Respiratory fatigue:

Respiratory fatigue (113 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.