Simvastatin and Tetany - a phase IV clinical study of FDA data

Summary:

Tetany is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, also take Omeprazole, and have Breast cancer.

The phase IV clinical study analyzes which people have Tetany when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Tetany?

Tetany (involuntary contraction of muscles) is found to be associated with 185 drugs and 449 conditions by eHealthMe. Check the latest studies of Tetany.

On Aug, 09, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 34 people (0.01%) have Tetany.

Among these 34 people:

What is the gender of people who have Tetany when taking Simvastatin? *

female: 85.29 %
male: 14.71 %

What is the age of people who have Tetany when taking Simvastatin? *

What are other drugs people take besides Simvastatin? *

Omeprazole: 21 people, 61.76%
Aspirin: 15 people, 44.12%
Docetaxel: 11 people, 32.35%
Dexamethasone: 11 people, 32.35%
Candesartan Cilexetil: 9 people, 26.47%
Acetaminophen: 8 people, 23.53%
Ramipril: 8 people, 23.53%
Cyclophosphamide: 7 people, 20.59%
Bisoprolol Fumarate: 6 people, 17.65%
Isosorbide Mononitrate: 6 people, 17.65%

What are other side effects people have besides Tetany? *

Hypocalcaemia (levels of calcium in blood serum are abnormally low): 21 people, 61.76%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 17 people, 50.00%
Diarrhea: 14 people, 41.18%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 6 people, 17.65%
Muscle Spasms (muscle contraction): 6 people, 17.65%
Blood Calcium Decreased: 5 people, 14.71%
Blood Magnesium Decreased: 3 people, 8.82%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 8.82%
Hypokalemia (low potassium): 3 people, 8.82%
Abdominal Discomfort: 3 people, 8.82%

What are the existing conditions these people have? *

Breast Cancer: 11 people, 32.35%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 26.47%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 11.76%
Pain: 3 people, 8.82%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 3 people, 8.82%
Cardiac Failure Chronic: 3 people, 8.82%
Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 2 people, 5.88%
Cough: 2 people, 5.88%
Diabetes: 2 people, 5.88%
Ovarian Cancer (cancer of ovary): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Tetany?

- Check whether Tetany is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,970 reports)

Tetany treatments and more:

Tetany (2,404 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tetany:

Tetany (185 drugs)

Browse all the conditions that are associated with Tetany:

Tetany (449 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.