Simvastatin and Thyroid gland removal - a phase IV clinical study of FDA data

Summary:

Thyroid gland removal is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Synthroid, and have Osteoporosis.

The phase IV clinical study analyzes which people have Thyroid gland removal when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Thyroid gland removal?

Thyroid gland removal is found to be associated with 218 drugs and 503 conditions by eHealthMe. Check the latest studies of Thyroid gland removal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 22 people (0.01%) have Thyroid gland removal.

Could Simvastatin cause Thyroid gland removal?

Among these 22 people:

How long have people been on Simvastatin when they have Thyroid gland removal? *

What is the gender of people who have Thyroid gland removal when taking Simvastatin? *

female: 90.48 %
male: 9.52 %

What is the age of people who have Thyroid gland removal when taking Simvastatin? *

What are other drugs people take besides Simvastatin? *

What are other side effects people have besides Thyroid gland removal? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 22.73%
Benign Neoplasm Of Thyroid Gland (benign (non-cancerous) tumours of the thyroid gland): 4 people, 18.18%
Bone Density Decreased: 3 people, 13.64%
Thermal Burn (burn by heat): 3 people, 13.64%
Blood Calcium Decreased: 3 people, 13.64%
Pancreatitis Acute (sudden inflammation of pancreas): 3 people, 13.64%
Corneal Dystrophy (abnormal deposition of substances in the transparent front part of the eye): 3 people, 13.64%
Oedema Peripheral (superficial swelling): 3 people, 13.64%
Burn Infection: 3 people, 13.64%
Upper Respiratory Tract Infection: 2 people, 9.09%

What are the existing conditions these people have? *

Diabetes: 4 people, 18.18%
Osteoporosis (bones weak and more likely to break): 4 people, 18.18%
Pain: 3 people, 13.64%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 13.64%
Insomnia (sleeplessness): 2 people, 9.09%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 9.09%
Type 2 Diabetes: 2 people, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.55%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Thyroid gland removal?

- Check whether Thyroid gland removal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,970 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid gland removal:

Thyroid gland removal (218 drugs)

Browse all the conditions that are associated with Thyroid gland removal:

Thyroid gland removal (503 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.