Simvastatin and Ulcer - a phase IV clinical study of FDA data

Summary:

Ulcer is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Aspirin, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Ulcer when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,961 Simvastatin users. Check the latest studies of Simvastatin.

What is Ulcer?

Ulcer is found to be associated with 2,664 drugs and 3,343 conditions by eHealthMe. Check the latest studies of Ulcer.

On Oct, 10, 2025

249,370 people reported to have side effects when taking Simvastatin.
Among them, 1,334 people (0.53%) have Ulcer.

Among these 1,334 people:

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Ulcer?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,961 reports)

Ulcer treatments and more:

Ulcer (113,570 reports)

How severe was Ulcer and when was it recovered:

Ulcer in Simvastatin

Expand to all the drugs that have ingredients of simvastatin:

Ulcer and drugs with ingredients of simvastatin (2,001 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Simvastatin side effects:

Simvastatin side effect: Nausea (feeling of having an urge to vomit) (13,681 reports)
Simvastatin side effect: Dyspnea (difficult or laboured breathing) (13,440 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Ulcer:

Aspirin side effect: Ulcer (4,680 reports)
Prednisone side effect: Ulcer (4,508 reports)
Methotrexate side effect: Ulcer (3,829 reports)
Humira side effect: Ulcer (3,538 reports)
Vioxx side effect: Ulcer (3,183 reports)
Profen side effect: Ulcer (3,021 reports)
Ibu side effect: Ulcer (3,008 reports)
Ibuprofen side effect: Ulcer (3,004 reports)
Fosamax side effect: Ulcer (2,526 reports)
Enbrel side effect: Ulcer (2,436 reports)

Browse all the drugs that are associated with Ulcer:

Ulcer (2,664 drugs)

Common conditions associated with Ulcer:

Ra: 5,033 reports
Rheumatoid arthritis: 5,021 reports
Hypertension: 3,877 reports
Htn: 3,856 reports
Pain exacerbated: 2,842 reports
Pain relief: 2,777 reports
Osteoporosis: 2,060 reports
Thin bones: 1,951 reports
Acupuncture and pain: 1,765 reports
Crohn's disease aggravated: 1,526 reports

Browse all the conditions that are associated with Ulcer:

Ulcer (3,343 conditions)

Drugs similar to Simvastatin and Ulcer :

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.