Simvastatin and Venous thrombosis - a phase IV clinical study of FDA data

Summary:

Venous thrombosis is reported as a side effect among people who take Simvastatin (simvastatin), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Pantoprazole, and have Diabetes.

The phase IV clinical study analyzes which people have Venous thrombosis when taking Simvastatin. It is created by eHealthMe based on reports of 249,370 people who have side effects when taking Simvastatin from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Venous thrombosis?

Venous thrombosis (blood clot (thrombus) that forms within a vein) is found to be associated with 556 drugs and 677 conditions by eHealthMe. Check the latest studies of Venous thrombosis.

On Aug, 09, 2026

249,370 people reported to have side effects when taking Simvastatin.
Among them, 75 people (0.03%) have Venous thrombosis.

Could Simvastatin cause Venous thrombosis?

Among these 75 people:

How long have people been on Simvastatin when they have Venous thrombosis? *

What is the gender of people who have Venous thrombosis when taking Simvastatin? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Venous thrombosis when taking Simvastatin? *

What are other drugs people take besides Simvastatin? *

What are other side effects people have besides Venous thrombosis? *

Pain In Extremity: 14 people, 18.67%
Pulmonary Embolism (blockage of the main artery of the lung): 14 people, 18.67%
Diarrhea: 14 people, 18.67%
Fever: 13 people, 17.33%
Fatigue (feeling of tiredness): 11 people, 14.67%
Weakness: 10 people, 13.33%
Nausea And Vomiting: 10 people, 13.33%
Thrombosis (formation of a blood clot inside a blood vessel): 10 people, 13.33%
Nausea (feeling of having an urge to vomit): 9 people, 12.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 10.67%

What are the existing conditions these people have? *

Diabetes: 7 people, 9.33%
Malignant Melanoma (skin cancer rises from melancytes): 6 people, 8.00%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 6 people, 8.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 8.00%
Cerebral Artery Occlusion (blockage of blood vessel of brain by fat or clot): 5 people, 6.67%
Birth Control: 5 people, 6.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 5.33%
Headache (pain in head): 4 people, 5.33%
Burkitt Lymphoma (cancer of the lymphatic system): 4 people, 5.33%
Thyroid Diseases: 4 people, 5.33%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Venous thrombosis?

- Check whether Venous thrombosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simvastatin:

Simvastatin (256,970 reports)

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Venous thrombosis:

Venous thrombosis (556 drugs)

Browse all the conditions that are associated with Venous thrombosis:

Venous thrombosis (677 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.