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Sitagliptin phosphate and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Sitagliptin phosphate (sitagliptin phosphate), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Metformin, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Sitagliptin phosphate. It is created by eHealthMe based on reports of 3,765 people who have side effects when taking Sitagliptin phosphate from the FDA, and is updated regularly.

What is Sitagliptin phosphate?

Sitagliptin phosphate has active ingredients of sitagliptin phosphate. eHealthMe is studying from 3,787 Sitagliptin phosphate users. Check the latest studies of Sitagliptin phosphate.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,957 drugs and 2,936 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

On Jul, 05, 2026

3,765 people reported to have side effects when taking Sitagliptin phosphate.
Among them, 87 people (2.31%) have Hyperkalemia.

Could Sitagliptin phosphate cause Hyperkalemia?

Among these 87 people:

How long have people been on Sitagliptin phosphate when they have Hyperkalemia? *

  • < 1 month: 7.69 %
  • 1 - 6 months: 15.38 %
  • 6 - 12 months: 30.77 %
  • 1 - 2 years: 46.15 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperkalemia when taking Sitagliptin phosphate? *

  • female: 42.68 %
  • male: 57.32 %

What is the age of people who have Hyperkalemia when taking Sitagliptin phosphate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 1.25 %
  • 40-49: 0.0 %
  • 50-59: 6.25 %
  • 60+: 92.5 %

What are other drugs people take besides Sitagliptin phosphate? *

  1. Metformin: 28 people, 32.18%
  2. Pantoprazole: 20 people, 22.99%
  3. Gliclazide: 16 people, 18.39%
  4. Esbriet: 12 people, 13.79%
  5. Furosemide: 12 people, 13.79%
  6. Glucophage: 12 people, 13.79%
  7. Allopurinol: 11 people, 12.64%
  8. Insulin: 11 people, 12.64%
  9. Metformin Hydrochloride: 11 people, 12.64%
  10. Amlodipine: 10 people, 11.49%

What are other side effects people have besides Hyperkalemia? *

  1. Dizziness: 19 people, 21.84%
  2. Dyspnea (difficult or laboured breathing): 17 people, 19.54%
  3. Nausea (feeling of having an urge to vomit): 16 people, 18.39%
  4. Acute Kidney Failure: 15 people, 17.24%
  5. Stress And Anxiety: 15 people, 17.24%
  6. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 14 people, 16.09%
  7. Lactic Acidosis (low ph in body tissues): 14 people, 16.09%
  8. Pneumonia: 14 people, 16.09%
  9. Weakness: 13 people, 14.94%
  10. Diarrhea: 13 people, 14.94%

What are the existing conditions these people have? *

  1. High Blood Pressure: 29 people, 33.33%
  2. Type 2 Diabetes: 19 people, 21.84%
  3. Diabetes: 18 people, 20.69%
  4. Depression: 15 people, 17.24%
  5. Idiopathic Pulmonary Fibrosis (chronic lung disease): 12 people, 13.79%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 11.49%
  7. High Blood Cholesterol: 10 people, 11.49%
  8. Cardiac Failure: 7 people, 8.05%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 6.90%
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Sitagliptin phosphate and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sitagliptin phosphate:

Hyperkalemia treatments and more:

How severe was Hyperkalemia and when was it recovered:

Expand to all the drugs that have ingredients of sitagliptin phosphate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sitagliptin phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Browse all the conditions that are associated with Hyperkalemia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on sitagliptin phosphate (the active ingredients of Sitagliptin phosphate) and Sitagliptin phosphate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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