Skelaxin and Gallbladder disease - a phase IV clinical study of FDA data

Summary:

Gallbladder disease is reported as a side effect among people who take Skelaxin (metaxalone), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Aspirin, and have Migraine.

The phase IV clinical study analyzes which people have Gallbladder disease when taking Skelaxin. It is created by eHealthMe based on reports of 8,840 people who have side effects when taking Skelaxin from the FDA, and is updated regularly.

What is Skelaxin?

Skelaxin has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 9,706 Skelaxin users. Check the latest studies of Skelaxin.

What is Gallbladder disease?

Gallbladder disease is found to be associated with 442 drugs and 1,006 conditions by eHealthMe. Check the latest studies of Gallbladder disease.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

8,840 people reported to have side effects when taking Skelaxin.
Among them, 14 people (0.16%) have Gallbladder disease.

Could Skelaxin cause Gallbladder disease?

Among these 14 people:

How long have people been on Skelaxin when they have Gallbladder disease? *

What is the gender of people who have Gallbladder disease when taking Skelaxin? *

female: 64.29 %
male: 35.71 %

What is the age of people who have Gallbladder disease when taking Skelaxin? *

What are other drugs people take besides Skelaxin? *

What are other side effects people have besides Gallbladder disease? *

Diarrhea: 6 people, 42.86%
Gallstones (stone formation by bile component): 6 people, 42.86%
Abdominal Pain Upper: 6 people, 42.86%
Nausea (feeling of having an urge to vomit): 6 people, 42.86%
Stress And Anxiety: 6 people, 42.86%
Head Injury: 5 people, 35.71%
Brain Herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull): 5 people, 35.71%
Cholecystitis Chronic (long lasting infection of gallbladder): 5 people, 35.71%
Consciousness - Decreased: 5 people, 35.71%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 5 people, 35.71%

What are the existing conditions these people have? *

Migraine (headache): 5 people, 35.71%
Birth Control: 4 people, 28.57%
Stress And Anxiety: 1 person, 7.14%
Insulin Resistance: 1 person, 7.14%
Back Injury: 1 person, 7.14%
Cardiac Disorder: 1 person, 7.14%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 7.14%
Depression: 1 person, 7.14%
Drowsiness: 1 person, 7.14%
Gastric Ulcer (stomach ulcer): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Skelaxin and have Gallbladder disease?

- Check whether Gallbladder disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Skelaxin:

Skelaxin (9,706 reports)

Browse all side effects of Skelaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallbladder disease:

Gallbladder disease (442 drugs)

Browse all the conditions that are associated with Gallbladder disease:

Gallbladder disease (1,006 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metaxalone (the active ingredients of Skelaxin) and Skelaxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.