Solu-cortef and Sinus congestion - a phase IV clinical study of FDA data

Summary:

Sinus congestion is reported as a side effect among people who take Solu-cortef (hydrocortisone sodium succinate), especially for people who are female, 50-59 old, also take Benadryl, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Sinus congestion when taking Solu-cortef. It is created by eHealthMe based on reports of 7,966 people who have side effects when taking Solu-cortef from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Sinus congestion?

Sinus congestion (blockage of sinus) is found to be associated with 1,007 drugs and 954 conditions by eHealthMe. Check the latest studies of Sinus congestion.

On Jul, 19, 2026

7,966 people reported to have side effects when taking Solu-cortef.
Among them, 14 people (0.18%) have Sinus congestion.

Could Solu-cortef cause Sinus congestion?

Among these 14 people:

What is the gender of people who have Sinus congestion when taking Solu-cortef? *

female: 100 %
male: 0.0 %

What is the age of people who have Sinus congestion when taking Solu-cortef? *

What are other drugs people take besides Solu-cortef? *

What are other side effects people have besides Sinus congestion? *

Fatigue (feeling of tiredness): 14 people, 100.00%
High Blood Pressure: 13 people, 92.86%
Weight Increased: 10 people, 71.43%
Nasopharyngitis (inflammation of the nasopharynx): 7 people, 50.00%
Abdominal Pain Upper: 7 people, 50.00%
Blood Pressure Fluctuation: 7 people, 50.00%
C-Reactive Protein Increased: 7 people, 50.00%
Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 7 people, 50.00%
Fever: 7 people, 50.00%
Abdominal Discomfort: 7 people, 50.00%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 7 people, 50.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 42.86%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-cortef and have Sinus congestion?

- Check whether Sinus congestion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Solu-cortef:

Solu-cortef (7,983 reports)

Sinus congestion treatments and more:

Sinus congestion (21,241 reports)

How severe was Sinus congestion and when was it recovered:

Sinus congestion in Solu-cortef

Expand to all the drugs that have ingredients of hydrocortisone sodium succinate:

Sinus congestion and drugs with ingredients of hydrocortisone sodium succinate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Solu-cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus congestion:

Sinus congestion (1,007 drugs)

Browse all the conditions that are associated with Sinus congestion:

Sinus congestion (954 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone sodium succinate (the active ingredients of Solu-cortef) and Solu-cortef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.