Sonata and Angina pectoris aggravated - a phase IV clinical study of FDA data

Summary:

Angina pectoris aggravated is reported as a side effect among people who take Sonata (zaleplon), especially for people who are female, 60+ old, also take Vioxx, and have Hyperlipidaemia.

The phase IV clinical study analyzes which people have Angina pectoris aggravated when taking Sonata. It is created by eHealthMe based on reports of 3,092 people who have side effects when taking Sonata from the FDA, and is updated regularly.

What is Sonata?

Sonata has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 3,330 Sonata users. Check the latest studies of Sonata.

What is Angina pectoris aggravated?

Angina pectoris aggravated (chest pain due to ischemia of the heart muscle) is found to be associated with 1,385 drugs and 644 conditions by eHealthMe. Check the latest studies of Angina pectoris aggravated.

On Jul, 07, 2026

3,092 people reported to have side effects when taking Sonata.
Among them, 27 people (0.87%) have Angina pectoris aggravated.

Could Sonata cause Angina pectoris aggravated?

Among these 27 people:

What is the gender of people who have Angina pectoris aggravated when taking Sonata? *

female: 53.85 %
male: 46.15 %

What is the age of people who have Angina pectoris aggravated when taking Sonata? *

What are other drugs people take besides Sonata? *

What are other side effects people have besides Angina pectoris aggravated? *

Anaemia (lack of blood): 14 people, 51.85%
Chest Pain: 14 people, 51.85%
Depression: 12 people, 44.44%
Nausea (feeling of having an urge to vomit): 11 people, 40.74%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 10 people, 37.04%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 10 people, 37.04%
Dizziness: 9 people, 33.33%
High Blood Pressure: 9 people, 33.33%
Pain: 9 people, 33.33%
Cardiac Murmur (an heart sound in valve abnormality): 8 people, 29.63%

What are the existing conditions these people have? *

Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 18.52%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 14.81%
Joint Pain: 3 people, 11.11%
Multiple Myeloma (cancer of the plasma cells): 2 people, 7.41%
High Blood Cholesterol: 2 people, 7.41%
Bipolar Disorder (mood disorder): 2 people, 7.41%
Pain: 2 people, 7.41%
Cardiac Failure Congestive: 2 people, 7.41%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.70%
Dizziness: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Sonata and have Angina pectoris aggravated?

- Check whether Angina pectoris aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sonata:

Sonata (3,330 reports)

Browse all side effects of Sonata:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (1,385 drugs)

Browse all the conditions that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (644 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zaleplon (the active ingredients of Sonata) and Sonata (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.