Spironolactone and Akinesia - a phase IV clinical study of FDA data

Summary:

Akinesia is reported as a side effect among people who take Spironolactone (spironolactone), especially for people who are male, 60+ old, also take Metformin, and have Cardiac failure acute.

The phase IV clinical study analyzes which people have Akinesia when taking Spironolactone. It is created by eHealthMe based on reports of 119,147 people who have side effects when taking Spironolactone from the FDA, and is updated regularly.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

What is Akinesia?

Akinesia (loss of control of voluntary muscle movements) is found to be associated with 315 drugs and 479 conditions by eHealthMe. Check the latest studies of Akinesia.

On Jul, 08, 2026

119,147 people reported to have side effects when taking Spironolactone.
Among them, 32 people (0.03%) have Akinesia.

Among these 32 people:

What is the gender of people who have Akinesia when taking Spironolactone? *

female: 20 %
male: 80 %

What is the age of people who have Akinesia when taking Spironolactone? *

What are other drugs people take besides Spironolactone? *

What are other side effects people have besides Akinesia? *

Mitral Valve Incompetence (inefficient heart valve): 15 people, 46.88%
Peripheral Swelling: 10 people, 31.25%
Cardiac Failure: 9 people, 28.12%
Ejection Fraction Decreased (systolic heart failure): 8 people, 25.00%
Left Ventricular Dysfunction: 8 people, 25.00%
Weight Decreased: 8 people, 25.00%
Oedema Peripheral (superficial swelling): 7 people, 21.88%
Weight Increased: 7 people, 21.88%
Brain Natriuretic Peptide Increased: 7 people, 21.88%
Ventricular Hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do): 7 people, 21.88%

What are the existing conditions these people have? *

Cardiac Failure Acute: 6 people, 18.75%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 12.50%
Cardiac Failure: 3 people, 9.38%
Cardiac Failure Congestive: 2 people, 6.25%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 3.12%
Hyperthyroidism (over activity of the thyroid gland): 1 person, 3.12%
Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 1 person, 3.12%
Heart Attack: 1 person, 3.12%
Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 3.12%
Diabetes: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Spironolactone and have Akinesia?

- Check whether Akinesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spironolactone:

Spironolactone (122,947 reports)

Akinesia treatments and more:

Akinesia (3,086 reports)

Browse all side effects of Spironolactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Akinesia:

Akinesia (315 drugs)

Browse all the conditions that are associated with Akinesia:

Akinesia (479 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Spironolactone) and Spironolactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.