Spironolactone and Lip disorder - a phase IV clinical study of FDA data

Summary:

Lip disorder is reported as a side effect among people who take Spironolactone (spironolactone), especially for people who are female, 60+ old, also take Furosemide, and have Diffuse large b-cell lymphoma refractory.

The phase IV clinical study analyzes which people have Lip disorder when taking Spironolactone. It is created by eHealthMe based on reports of 119,147 people who have side effects when taking Spironolactone from the FDA, and is updated regularly.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

What is Lip disorder?

Lip disorder (disease of lip) is found to be associated with 291 drugs and 406 conditions by eHealthMe. Check the latest studies of Lip disorder.

On Aug, 12, 2026

119,147 people reported to have side effects when taking Spironolactone.
Among them, 11 people (0.01%) have Lip disorder.

Could Spironolactone cause Lip disorder?

Among these 11 people:

What is the gender of people who have Lip disorder when taking Spironolactone? *

female: 63.64 %
male: 36.36 %

What is the age of people who have Lip disorder when taking Spironolactone? *

What are other drugs people take besides Spironolactone? *

Furosemide: 4 people, 36.36%
Bactrim: 3 people, 27.27%
Lotrimin: 3 people, 27.27%
Melatonin: 3 people, 27.27%
Ondansetron: 3 people, 27.27%
Pantoprazole: 3 people, 27.27%
Potassium Phosphates: 3 people, 27.27%
Allopurinol: 3 people, 27.27%
Baclofen: 2 people, 18.18%
Tramadol Hydrochloride: 2 people, 18.18%

What are other side effects people have besides Lip disorder? *

Acute Kidney Failure: 3 people, 27.27%
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 3 people, 27.27%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 27.27%
Infection: 3 people, 27.27%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 3 people, 27.27%
Encephalopathy (functioning of the brain is affected by some agent or condition): 3 people, 27.27%
Mycobacterium Abscessus Infection (rapid growing bacterial infection): 3 people, 27.27%
Erythema Multiforme (a type of hypersensitivity reaction): 3 people, 27.27%
Speech Impairment (Adult) (inability to speak (adult)): 3 people, 27.27%
Acute Respiratory Failure: 3 people, 27.27%

What are the existing conditions these people have? *

Diffuse Large B-Cell Lymphoma Refractory (cancer of b cells, a type of white blood cell-relapsed): 3 people, 27.27%
Type 2 Diabetes: 1 person, 9.09%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 9.09%
Diabetes: 1 person, 9.09%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 9.09%
Affective Disorder (mental disorder): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Spironolactone and have Lip disorder?

- Check whether Lip disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spironolactone:

Spironolactone (122,947 reports)

Lip disorder treatments and more:

Lip disorder (2,297 reports)

Browse all side effects of Spironolactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lip disorder:

Lip disorder (291 drugs)

Browse all the conditions that are associated with Lip disorder:

Lip disorder (406 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Spironolactone) and Spironolactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.