Strensiq and Rickets - a phase IV clinical study of FDA data

Summary:

Rickets is reported as a side effect among people who take Strensiq (asfotase alfa), especially for people who are female, 2-9 old, have been taking the drug for 2 - 5 years also take Emla, and have Hypophosphatasia.

The phase IV clinical study analyzes which people have Rickets when taking Strensiq. It is created by eHealthMe based on reports of 7,139 people who have side effects when taking Strensiq from the FDA, and is updated regularly.

What is Strensiq?

Strensiq has active ingredients of asfotase alfa. eHealthMe is studying from 7,141 Strensiq users. Check the latest studies of Strensiq.

What is Rickets?

Rickets (softening of bones) is found to be associated with 1,092 drugs and 1,458 conditions by eHealthMe. Check the latest studies of Rickets.

On Jul, 17, 2026

7,139 people reported to have side effects when taking Strensiq.
Among them, 31 people (0.43%) have Rickets.

Among these 31 people:

How long have people been on Strensiq when they have Rickets? *

What is the gender of people who have Rickets when taking Strensiq? *

female: 70.37 %
male: 29.63 %

What is the age of people who have Rickets when taking Strensiq? *

What are other drugs people take besides Strensiq? *

What are other side effects people have besides Rickets? *

Drug Ineffective: 8 people, 25.81%
Vitamin B6 Increased: 7 people, 22.58%
Fatigue (feeling of tiredness): 7 people, 22.58%
Blood Alkaline Phosphatase Decreased: 7 people, 22.58%
Blood Alkaline Phosphatase Increased: 7 people, 22.58%
Loose Tooth: 7 people, 22.58%
Joint Pain: 6 people, 19.35%
Craniosynostosis (a baby is born with an abnormally shaped skull or develops one during growth): 6 people, 19.35%
Eczema Asteatotic (severe dry skin- during the winter months and in the elderly): 6 people, 19.35%
Nephrocalcinosis (a condition in which calcium levels in the kidneys are increased): 5 people, 16.13%

What are the existing conditions these people have? *

Hypophosphatasia (metabolic bone disease): 30 people, 96.77%
Pain In Extremity: 3 people, 9.68%
Joint Pain: 3 people, 9.68%
Back Pain: 3 people, 9.68%
Agitation (state of anxiety or nervous excitement): 2 people, 6.45%
Sputum Retention: 1 person, 3.23%
Nausea And Vomiting: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Strensiq and have Rickets?

- Check whether Rickets is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Strensiq:

Strensiq (7,141 reports)

Rickets treatments and more:

Rickets (30,776 reports)

Browse all side effects of Strensiq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rickets:

Rickets (1,092 drugs)

Browse all the conditions that are associated with Rickets:

Rickets (1,458 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on asfotase alfa (the active ingredients of Strensiq) and Strensiq (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.