Sulfamethoxazole and Generalised oedema - a phase IV clinical study of FDA data

Summary:

Generalised oedema is reported as a side effect among people who take Sulfamethoxazole (sulfamethoxazole), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Amoxicillin, and have Depression.

The phase IV clinical study analyzes which people have Generalised oedema when taking Sulfamethoxazole. It is created by eHealthMe based on reports of 13,142 people who have side effects when taking Sulfamethoxazole from the FDA, and is updated regularly.

What is Sulfamethoxazole?

Sulfamethoxazole has active ingredients of sulfamethoxazole. It is often used in urinary tract infection. eHealthMe is studying from 13,360 Sulfamethoxazole users. Check the latest studies of Sulfamethoxazole.

What is Generalised oedema?

Generalised oedema (swelling all over the body) is found to be associated with 1,091 drugs and 1,405 conditions by eHealthMe. Check the latest studies of Generalised oedema.

On Jul, 07, 2026

13,142 people reported to have side effects when taking Sulfamethoxazole.
Among them, 32 people (0.24%) have Generalised oedema.

Could Sulfamethoxazole cause Generalised oedema?

Among these 32 people:

How long have people been on Sulfamethoxazole when they have Generalised oedema? *

What is the gender of people who have Generalised oedema when taking Sulfamethoxazole? *

female: 29.03 %
male: 70.97 %

What is the age of people who have Generalised oedema when taking Sulfamethoxazole? *

What are other drugs people take besides Sulfamethoxazole? *

Amoxicillin: 17 people, 53.12%
Ibuprofen: 15 people, 46.88%
Lantus: 10 people, 31.25%
Levaquin: 9 people, 28.12%
Chlorpheniramine Maleate: 9 people, 28.12%
Vancomycin: 9 people, 28.12%
Gabapentin: 9 people, 28.12%
Paxil: 9 people, 28.12%
Albuterol: 9 people, 28.12%
Levetiracetam: 8 people, 25.00%

What are other side effects people have besides Generalised oedema? *

Stress And Anxiety: 18 people, 56.25%
Pain: 17 people, 53.12%
Nausea (feeling of having an urge to vomit): 13 people, 40.62%
Anaemia (lack of blood): 13 people, 40.62%
Diarrhea: 12 people, 37.50%
Fever: 12 people, 37.50%
Dyspnea (difficult or laboured breathing): 11 people, 34.38%
Neuropathy Peripheral (surface nerve damage): 11 people, 34.38%
Swelling: 10 people, 31.25%
Pain In Extremity: 10 people, 31.25%

What are the existing conditions these people have? *

Depression: 9 people, 28.12%
High Blood Pressure: 6 people, 18.75%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 12.50%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.50%
Oedema (fluid collection in tissue): 4 people, 12.50%
Diabetes: 4 people, 12.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 12.50%
Stable Angina (a constant chest pain): 4 people, 12.50%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Sulfamethoxazole and have Generalised oedema?

- Check whether Generalised oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sulfamethoxazole:

Sulfamethoxazole (13,360 reports)

Browse all side effects of Sulfamethoxazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Generalised oedema:

Generalised oedema (1,091 drugs)

Browse all the conditions that are associated with Generalised oedema:

Generalised oedema (1,405 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole (the active ingredients of Sulfamethoxazole) and Sulfamethoxazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.